Department of Pathology @ Ospedale San Raffaele
Mission of the Pathology Unit has three aims: diagnostic, scientific and didactic activities. Diagnostic activity is our first mission. We provide histopathological, cytopathological and molecular diagnosis for San Raffaele Hospital, as well as outservice for several other hospitals of GSD Group and other external Clinics. We receive also several cases from patients seeking a second expert opinion. The role of diagnostic pathology has moved from basic morphological observation to comprehensive tissue analysis through combined histological, immunohistochemical and molecular evaluations. Accordingly, novel scientific achievements and technologies have been translated into useful clinical tests that provide a molecular fingerprint of diseases and that are predictive of the response to treatment. In our daily work we utilize these tools into diagnostic, prognostic, and therapeutic applications. This approach involves yearly around 90.000 cases per year with a constant increasing trend. Our Medical Staff covers all the areas of Pathology with individual expertises in different fields. The histopathology lab is fully equipped with most updated instruments and is moving to diagnostics fully performed with whole digital slides - Digital Pathology.
The Oncologic Molecular Diagnostics Laboratory of our Unit is an accredited and certified multidisciplinary laboratory devoted to provide patients and clinicians with comprehensive and accurate molecular testing. Our laboratory performs a wide range of DNA and RNA based tests for solid tumors, hematologic malignancies and infectious diseases, utilizing a wide spectrum of molecular techniques and platforms to evaluate nucleic acids isolated from patient samples, including tissues, fluids and blood, for a comprehensive assessement of altered genes associated with solid and hematopoietic tumors, including lung, colon, breast, melanoma, pancreatic, and ovarian cancers as well lymphoid and hematological malignanci, for which approved targeted therapies are already available.
Conditions we take care of at this Department
Notable advanced technological equipment
- High Capacity Digital Scanners for Digital Pathology;
- NGS Instruments for Diagnostic Molecular Oncology;
- 4 Benchmark Ultra and 1 Discovery Roche Ventana Instruments for immunohistochemistry, including multiplex immunfluorescence: Zeiss Metafer Slide Scanning Platform system for FISH automation.