Multiple endocrine neoplasia (MEN) and endocrine tumors
How is it diagnosed?
How is it treated?
In forms with a genetic predisposition, there is a 50 percent risk that the affected parent will pass the disease to his or her offspring in every pregnancy.
This implies the need of:
- early diagnostics;
- testing family members with endocrinology tests to detect the presence of asymptomatic hyperplasia/neoplasia and genetic tests to identify carriers of the diseased gene;
- diagnostic and therapeutic monitoring.
A major difficulty in the clinical management of patients with multiple endocrine neoplasms and endocrine tumors is identifying symptoms that are often not present or when patients are carriers of rare clinical syndromes and therefore cannot be easily identified.
T.E.A.M., a group for the study and treatment of endocrine tumors using a multidisciplinary approach, has been established at the San Raffaele Hospital. Its goal is to ensure that the patient has a definite and effective diagnostic and therapeutic pathway.
The second problem is the need to monitor the clinical situation of family members who may be carriers of these diseases or genetic mutations. To this end, the Oncologic Endocrinology/Endocrine Tumor Clinic/MEN Outpatient Clinic led by T.E.A.M. has been established to provide a program of diagnostic and therapeutic care for both patients undergoing treatment and their families.