Department of Cardiac Surgery @ Ospedale San Raffaele

The Cardiac Surgery Unit of Ospedale San Raffaele performs approximately 1.400 cardiac surgery procedures each year, covering the widest spectrum of heart pathologies. The Unit is the centre of national and international reference for the surgical repair of the mitral valve, for the atrial fibrillations, and for heart failure surgeries. It is also a national reference centre for the beating heart coronary surgery. Minimally invasive surgical techniques are performed with optimal technological support, including robotic.

Multidisciplinary consultations within the Cardio-Thoracic-Vascular area are available in collaboration with other units of Ospedale San Raffaele.

A notable Division of Cardiac Surgery of Advanced and Research Therapies carries out its activity within the Cardiac Surgery Unit and is headed by Professor Michele De Bonis. Clinical and translational research is an essential element for a cutting-edge centre, that considers "patient-centred care" as its guiding principle, in order to identify and propose, in a multidisciplinary setting, the most suitable solution for the individual patient.

Our excellence in numbers


procedures each year


mitral valve repair procedures

Notable advanced technological equipment

  • One fully equipped hybrid operative room for open heart surgery and transcatheter interventions
  • Two Storz endoscope video systems for minimally invasive interventions
  • One GE Vivid E95 4D echo machine

Available surgical devices:

  • MitraClip transcatheter system for mitral valve repair
  • MitraClip transcatheter system for tricuspid valve repair (experimental)
  • Tiara transapical system for mitral valve replacement (experimental)
  • Tendyne transapical system for mitral valve replacement (experimental)
  • Cardiovalve transcatheter system for mitral valve replacement (experimental)
  • Perceval sutureless aortic valve prosthesis
  • Cobra Fusion catheter for surgical ablation of atrial fibrillation
  • E-vita hybrid stent graft for aorta replacement

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Meet our team

Head physician

Francesco Maisano

Cardiac Surgeon
Francesco Maisano

Featured physicians

Ospedale San Raffaele

The San Raffaele Research Hospital is a highly specialized multi-disciplinary medical center of world importance, which embodies the integrity of the treatment, clinical research and teaching activities. San Raffaele provides treatment in all existing medical fields, which allows this center to take care of the most complex patient cases. The Hospital is recognized as IRCCS (Scientific Institute for Research and Healthcare) for its research in molecular medicine and innovative treatments application, such as the gene therapy.

The hospital is a multi-specialty center with more than 50 clinical specialties available and with over 1600 beds; it is accredited by the Italian National Health System to provide care to both public and private, Italian and international patients. In 2018 the San Raffaele Hospital performed over 51,000 patient admissions, 72,000 emergency room encounters and delivered over 1.5 million outpatient medical services. It is widely regarded as the most celebrated hospital in the country and among the most reputable medical centers in Europe. San Raffaele’s wards and operating theatres are equipped with the most advanced machines, such as PET, PET/CT, Gamma Knife, Cyber Knife, Rapid Arc, Tomotherapy. San Raffaele’s Radiotherapy Unit was the first place in Europe to install Tomotherapy in 2004. Nowadays this Unit confirms to be one of the most experienced worldwide; it has developed numerous protocols for cancer treatment of the prostate, breast, central nervous system, brain, liver, pancreas, gastrointestinal tract, lungs, and others. The Oncological Board of the Hospital consisting of diagnosticians, clinical oncologists, immunologists, surgeons and radiotherapists, hold weekly meetings to discuss oncological patients’ pathways in a multidisciplinary manner.

Beside its Cancer Center, San Raffaele is well-known for its medical know-how in cardiology and cardiac surgery, neurology and neurosurgery, gastroenterology and gastrointestinal tract surgery, liver surgery, pancreas surgery, transplant medicine, gynecology and obstetrics, urology, dermatology, ophthalmology, immunology, rheumatology and pediatrics.

San Raffaele is a pioneer in the field of gene medicine and treatment of rare immunologic and genetic diseases. San Raffaele Scientific Institute is where the first in the world gene therapy with stem cells was created, named Strimvelis, for patients affected by ADA-SCID syndrome.

The Research at the San Raffaele Hospital focuses on integrating basic, translational and clinical research to provide the most advanced care to the patients. It counts on over 1,500 scientists, working in state-of-the-art facilities covering a surface of 130,000 square meters, and have produced over 1,446 scientific publications in 2018. Research at San Raffaele aims at understanding the mechanisms underlying a variety of important human diseases and at identifying new targets and new therapeutic strategies to treat them.

The San Raffaele Hospital hosts the Università Vita-Salute San Raffaele, a fully private university with a complete Medical School (including specialty courses and residencies), Nursing School, a Psychology graduate and post-graduate programs, and Allied Health Professions School. The mission of the Vita-Salute San Raffaele University is to answer the question "Quid est homo?" in the belief that the human being is a biological, psychological and spiritual unicum. Since 2010 the San Raffaele Hospital also hosts the International MD Program, the only graduate program accredited to license Medical Doctors in both Europe and North America.


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