Department of Orthopedics and Traumatology @ Ospedale Galeazzi - Sant'Ambrogio

Team C.A.S.C.O operates at the Galeazzi Research Hospital in Milan and was founded in 2010 by an initiative of Dr. Nicola Ursino. To date it consists of 12 specialists.

Every year it performs on average 1450 prosthetic interventions and 1550 minor orthopaedic interventions such as arthroscopy, ligaments and more, for a total of about 3000 interventions per year.
The Unit helps people with degenerative or traumatic articular disability to recover mobility and return to having an excellent quality of life.
The C.A.S.C.O. Unit today is a specialised division in the prosthetic reconstruction of the lower limb and has widened its field of interest to the upper limb, the foot and to the ankle prosthetics.

Ongoing studies include the evaluation of: 

  • Anti-allergic prosthesis (Bioloy) and bacterial biofilm: the first study in Europe to analyse its relationship in terms of reduction of infectious risk. 
  • Hypoallergenic prostheses (Vital-xe): polyethylene is also enriched with Vitamin-E which gives it anti-oxidant power and therefore a longer life over the years. 

These materials represent the latest evolution of engineering applied to prosthetic surgery.

Our excellence in numbers


prosthetic surgeries


knee total replacement


unicompartmental knee replacements


hip replacements


knee replacement revision surgeries


hip replacement revision surgeries

Notable advanced technological equipment

  • Adipose-derived stem cells                                                                
  • Anti-allergic knee and hip replacement added with vitamin E
  • Metal-on-metal hip revision
  • Ankle replacement with trans fibular osteotomy   

Do you need an appointment?

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Meet our team

Head physician

Nicola Ursino

Orthopedic surgeon
Nicola Ursino

Featured physicians

Ospedale Galeazzi - Sant'Ambrogio

The new hospital brings together in a single facility Istituto Ortopedico Galeazzi, the first hospital for orthopaedic admissions that performs 75% of all revision orthopaedic surgeries in Italy, and Istituto Clinico Sant'Ambrogio, example of healthcare excellence for its cardiovascular unit as well as for the diagnosis and treatment of obesity.

The new Ospedale Galeazzi - Sant’Ambrogio (OGSA), accredited by the Italian National Healthcare System (SSN), and given an IRCCS status (Scientific Institute for Research, Hospitalization and Healthcare) by the Italian Ministry of Health for the study of the locomotor system disorders, it is a center of excellence for clinical and pre-clinical biomedical research, and it is well-known for its teaching activity as a learning site for the Bachelor of Medicine and Surgery in agreement with the University of Milan.

As former Istituto Ortopedico Galeazzi, it is known for its achievements in the field of sports medicine and is now home for RE.GA.IN, a regenerative medicine center for the treatment of cartilage and tendon pathologies.

Since 2007, the Institute has become a member of the ISOC (International Society of Orthopaedic Centers), recognized as one of the 19 institutes of excellence in the field of orthopaedics representing 16 countries.

Former Istituto Clinico Sant'Ambrogio adds to the new OGSA its healthcare excellence in treatment of cardiovascular pathologies with over 500 interventions of cardiac surgery and 2,500 interventional cardiology procedures per year thus becoming among the first Italian centers for cardiovascular treatments. The Cardiothoracic Center represents a point of excellence in mini-invasive cardiac surgery and in the percutaneous aortic valve replacement. Additionally, former Istituto Clinico Sant'Ambrogio is in the first place among the Lombardy hospitals for the treatment of acute myocardial infarction.