Joint degeneration (Artrosi)
Which are the symptoms?
Increased friction makes the joints less elastic and flexible, resulting in symptoms such as pain, crepitus, swelling, stiff joints and loss of mobility. The symptoms depend on the severity of the damage to the cartilage.
- pain (arthralgia)
- creaking or squeaking in the joints
- feeling of warmth
- functional limitation
- morning stiffness in the joints
How is it diagnosed?
The main role in the diagnosis of cartilage disease is played by a clinical examination performed by an orthopaedic surgeon, during which the general condition of the joint is assessed. The clinical examination also gives the specialist the opportunity to check the symptoms directly with the patient. The imaging tools commonly used to diagnose these diseases are standard radiographs (traditional radiology remains a fundamental and indispensable method) and magnetic resonance imaging, which has become an increasingly popular method in recent years.
How is it treated?
The human body is capable of spontaneous healing through normal tissue healing processes involving growth factors and cellular elements with a regenerative function. When these processes do not work, it is possible to resort to advanced technologies that "mimic" physiological healing processes. Regenerative medicine is an interdisciplinary field that combines research and the clinic and uses the therapeutic potential of the body to promote regeneration and restore the physiological condition of tissues affected by disease, injury and aging. Regenerative medicine differs from, for example, transplantation or substitute medicine in that its goal is not to replace what can no longer function in the human body, but to provide the necessary elements to stimulate and support the body's normal healing processes, which, in the case of arthritis, are impaired by the inflammatory state characteristic of the disease. This is made possible using therapeutic agents that are normally already present in the human body, such as platelet-derived growth factors (PRP) and mesenchymal cells derived from bone marrow and adipose tissue (MSC).
RE.GA.IN is a center of excellence that provides a clinical platform to ensure the best possible experience in regenerative medicine. Patients’ data are collected over a long period of time using the most modern standard operative procedure and then interpreted to identify the most performing treatment for a given indication. REGAIN treats the patients only with selected medical devices, paying attention to their scientific quality and safety profile. RE.GA.IN's activities are supported by the Research Laboratories of the Galeazzi Research Hospital to ensure a full characterization of the biological products produced in a custom manner for each patient.