Reiter's syndrome and reactive arthritis
Causes and risk factors
The cause is unknown. Often, rheumatoid arthritis is familial in nature, which proves a genetic predisposition to joint damage. About 74% of patients share a common genetic marker - the HLA-B27 molecule.
The disease is rare and most often affects male patients (the ratio of men to women is about 25 to 1). However, in women, the diagnosis may be complicated due to the difficulty of recognizing cervicitis.
The first symptoms are more common between the ages of 20 and 40. However, cases of reactive arthritis (usually post-enteritis) have also been reported in children and people over the age of eighty.
Which are the symptoms?
The most frequent manifestations:
skin rashes (similar to psoriasis);
malaise during urination (pain and discomfort during urination, urethral discharge)
How is it diagnosed?
How is it treated?
Treatment is carried out with non-steroidal anti-inflammatory drugs.
Therapy is based on taking sulfasalazine, although it may have limited benefits for spinal and sacroiliac joint damage.
In chronic and more severe forms, biological drugs (TNFα inhibitors) can be used.
The course of the disease is often unpredictable. Periods of exacerbation are often asymptomatic. The disease often becomes chronic with a progressive clinical course.