How is it diagnosed?
The diagnosis is clinical and is based on the presence of night blindness and on the identification of the Mizuo-Nakamura phenomenon by biomicroscopic examination of the fundus and ERG, which shows a normal response of the cones, while the response of rods after several minutes of adaptation to darkness changes greatly. The change may regress once the Mizuo-Nakamura phenomenon is established.
How is it treated?
There is currently no specific treatment for Oguchi disease.
Visual prognosis is favorable in the absence of progression of symptoms, although Oguchi disease is considered a permanent condition, it can cause decreased visual acuity or narrowing of the visual field, especially in elderly patients.