Giovanni Meola

Specialty:
Profession:
Neurologist
Languages:
EN
IT
FR

Biography

Professor Giovanni Meola held the position of Head of the Department of Neurology at the IRCCS Policlinico San Donato in Milan, Professor of Neurology since 2001, and since 2013 – Director of the Graduate School of Neurology of the University of Milan.

In 1973, he graduated from the Faculty of Medicine and Surgery at the University of Milan, where he received a specialization in neurology. His scientific and clinical training is being improved abroad, at British and North American universities, such asNewcastle upon Tyne General Hospital Regional Neurological Centre, College of Surgeons and PhysiciansColumbia University in New York and Houston Merritt Clinical Research Center for the Study of Muscular Dystrophy and Related Diseases. Since 1988, he has participated annually in the dell'American Academy of Neurology training courses (AAN) in the USA. In April 2007, he completed a clinical internship at the Mayo Stroke Center - Neurological Intensive Care Unit (Mayo Clinic, Rochester, MN, USA).

Since 1990, Professor Meola has been invited to prestigious foreign universities both as a speaker and for clinical teaching activities for neurologists. In particular, he is a visiting professor at the Department of Neurology, University of Rochester, a member of the Muscle Study Group (MSG), and since 2009 has been a visiting professor at the University of Belgrade (Serbia). Since 1995 he has been a speaker on clinical cases at the Neuromuscular Courses of the dell'American Academy of Neurology, and in 2010 he was appointed head and speaker of the course "Update of Myotonias" at the American Academy of Neurology (AAN). He has delivered 270 courses of lectures by invitation in Italy and abroad.

In the IRCCS Policlinico San Donato from 1992 to 2019, as head of the Department of Neurology, he created the Department of Stroke and heads the Laboratory of Muscular Histopathology and Molecular Biology of Neuromuscular Diseases. In 2015, he was also appointed head of the National Register of Myotonic Dystrophy, funded by the Ministry of Health. 
Since 1991, Professor Meola has been conducting research funded by national and international projects (MURST, FIRST, PRIN, Telethon, AFM Telethon, MDF, Ministry of Health). These studies have resulted in 254 publications in journals cited by JCR (Journal Citation Report), IM (Index Medicus), as well as an international board and reviewer; 66 articles published in national and international journals, and more than 480 abstracts presented at national and international conferences. Professor Meola has also written 41 chapters, 25 of which have been published in international papers. The impact factor of scientific publications is 822,229 with a Hirsch index of 37 with 5,122 citations for 233 documents (from 2003 to 2018).

He is the editor-in-chief of Frontiers in Neurology and the executive editor of Neuromuscular Disorders. He is also the founder and president of the Center for the Study of Neuromuscular Diseases (CMN), the Foundation for Myotonic Diseases (FMM) and since 2013 a member of the Ethics Committee of Ospedale San Raffaele.

Read moreRead less

Education

University of Milan
Diploma in Medicine and Surgery - 1973

University of Milan
Specialization in Neurology - 1977

Do you need an appointment?

Contact us and we will take care of you.

Publications

Latest publications

Mexiletine for Symnptoms and signs of Myotonia in Nondystrophic myotonia
JAMA 2012, October 3; Vol 308 (13)
Statland JM, Bundy BN, Wang Y, Rayan DR, Trivedi JR, Sansone V, Salajegheh MK, Venance SL, Ciafaloni E, Matthews E, Meola G, Herbelin L, Griggs RC, Barohn RJ, Hanna MG
Co-segregation of DM2 with a recessive CLCN1 mutation in juvenile onset of myotonic dystrophy type 2
J Neurol 2012;259(10):2090-9
Cardani R, Giagnacovo M, Botta A, Rinaldi F, Morgante A, Udd B, Raheem OR, Pentila S, Suominen T, Renna LV, Sansone V, Bugiardini E, Novelli G, Meola G.
GSK3β mediates muscle pathology in myotonic dystrophy
J Clin Invest 2012;122:4461-72
Jones K, Wei C, Iakova P, Bugiardini E, Schneider-Gold C, Meola G, Woodgett J,Killian J, Timchenko NA, Timchenko LT.
Plasma microRNAs as biomarkers for myotonic dystrophy type 1
Neuromuscul Disord 2014;24:509-15
Perfetti A, Greco S, Bugiardini E, Cardani R, Gaia P, Gaetano C, Meola G, Martelli F.
Progression of muscle histopathology but not of spliceopathy in myotonic dystrophy type 2
Neuromuscul Disord 2014;24:1042-53
Cardani R, Giagnacovo M, Rossi G, Renna LV, Bugiardini E, Pizzamiglio C, Botta A, Meola G.
RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1
PLoS One. 2014 Sep 11;9(9):e107324. doi: 10.1371/journal.pone.0107324. eCollection 2014.
Klinck R, Fourrier A, Thibault P, Toutant J, Durand M, Lapointe E, Caillet-Boudin ML, Sergeant N, Gourdon G, Meola G, Furling D, Puymirat J, Chabot B.
Reduction of toxic RNAs in myotonic dystrophies type 1 and type 2 by the RNA helicase p68/DDX5
Proc Natl Acad Sci U S A. 2015;112:8041-5
Jones K, Wei C, Schoser B, Meola G, Timchenko N, Timchenko L.
Myotonic Dystrophy type 2: an update on clinical aspects, genetic and pathomolecular mechanism
BBA-MOL BASIS DIS. 2015;1852:594-606
Meola G and Cardani R.
Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis
Neurology. 2016;86(15):1408-16
Sansone VA, Burge J, McDermott MP, Smith PC, Herr B, Tawil R, Pandya S, Kissel J, Ciafaloni E, Shieh P, Ralph JW, Amato A, Cannon SC, Trivedi J, Barohn R, Crum B, Mitsumoto H, Pestronk A, Meola G, Conwit R, Hanna MG, Griggs RC.
"I Know that You Know that I Know": Neural Substrates Associated with Social Cognition Deficits in DM1 Patients
PLoS One. 2016 Jun 3;11(6):e0156901
Serra L, Cercignani M, Bruschini M, Cipolotti L, Mancini M, Silvestri G, Petrucci A, Bucci E, Antonini G, Licchelli L, Spanò B, Giacanelli M, Caltagirone C, Meola G, Bozzali M.
Myotonic Dystrophies: State of the Art of New Therapeutic Developments for the CNS
Front Cell Neurosci. 2017 Apr 20;11:101.
Gourdon G, Meola G.
Biomolecular diagnosis of myotonic dystrophy type 2: a challenging approach
J Neurol 2017;264:1705-1714 Review
Meola G, Biasini F, Valaperta R, Costa E, Cardani R.
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
Nat Commun. 2018 May 22;9(1):2009
Sellier C, Cerro-Herreros E, Blatter M, Freyermuth F, Gaucherot A, Ruffenach F, Sarkar P, Puymirat J, Udd B, Day JW, Meola G, Bassez G, Fujimura H, Takahashi MP, Schoser B, Furling D, Artero R, Allain FHT, Llamusi B, Charlet-Berguerand N.
SCN4A as modifier gene in patients with myotonic dystrophy type 2
Sci Rep 2018;8:11058
Binda A, Renna LV, Bosè F, Brigonzi E, Botta A, Valaperta R, Fossati B, Rivolta I, Meola G, Cardani R.
Consensus-based care reccomendations for adults with myotonic dystrophy type 1
Neurology: clinical Practice. 2018;8:1-14
Ashizawa T, Gagnon C, Groh WJ, MPH, Gutmann L, Johnson NE, Meola G, Moxley III R, Pandya S, Rogers MT, Simpson E, Angeard N, Bassez G, Berggren KN, Bhakta M, Bozzali M, Broderick A, Byrne JLB, Campbell C, Day GW, De Mattia E, Duboc D, Duong T, Eichinger K, Ekstrom A-B, van Engelen B, Esparis B, Eymard B, Ferschl M, Gadalla SM, Gallais B, Goodglick T, Heatwole C, Hilbert J, Holland V, Kierkegaard M

Do you need an appointment?

Contact us and we will take care of you.