Alessandro Pini


Dr. Alessandro Pini is the Head of the Vascular Cardiogenetics Center at the IRCCS Policlinico San Donato in Milan.

In 1981 he graduated from the Faculty of Medicine and Surgery of the University of Milan, where in 1987 he received a specialization in internal medicine, and in 1991 - a specialization in cardiology. In 1994, he received a Master's degree in Health Organization for Primary Health Care and Inpatient Care from the Bocconi School of Management, and in 2003 he received a master's degree in Health Organization for second-level medical managers from the IREF of the Lombardy region.

In 1999, Dr. Pini founded the Marfan Clinic, the current headquarters of which is located in the IRCCS Policlinico San Donato. In the period from 2005 to 2008, he was the national cardiologist-referent for the evaluation of patient care projects and research of patients suffering from dystrophinopathy. He was also an adjunct professor at the University of Milan in the course of Medicine and Surgery, the School of Specialization in Pediatrics and the course of high specialization in Rare Diseases.

He is a referent and founding member of the European Network of Rare Vascular Diseases (VASCERN): in this area he coordinated the Digital Medicine Group for innovation of health strategies. Dr. Pini is also the contact person for operational coordination and exchange of common strategies in the field of rare diseases at the Regional Coordination Center for Rare Diseases (Mario Negri Institute). Since 2010, he has been a scientific referent and coordinator of the popular science initiatives of J Peter Onlus on Marfan syndrome and concomitant pathologies.

Since 2019, at the IRCCS Policlinico San Donato, he has been heading the Cardiogenetic Vascular Center, a national and international reference center for rare cardiovascular diseases, in particular thoracic aorta and large, medium and small-caliber arteries.

He is engaged in clinical and genetic diagnosis and follow-up of patients suffering from hereditary aortic and cardiac diseases that affect both children and adults. These conditions include both syndromic diseases (Marfan syndromes, Ehlers-Danlos vascular syndromes and Loys-Dietz, Fabry, Biles syndromes) and non-syndromic diseases (bicuspid aortic valve, aneurysm and familial dissections of the thoracic aorta, spontaneous artery dissections). The Center for Cardiovascular Genetics annually examines more than 1,200 patients, conducts more than 8000 diagnoses and 400 genetic tests.

Dr. Alessandro Pini conducts important research activities, which result in numerous scientific publications and 25 research programs currently being implemented, in which more than 30 researchers work in 7 research groups in cooperation with the Center.

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