Which are the symptoms?
Cockayne syndrome has a wide range of symptoms and severity. Patients have skin, neurological and somatic disorders. Skin photosensitivity occurs in about three quarters of affected patients. Unlike patients with xeroderma pigmentosa, patients with Cockayne syndrome do not show a predisposition to skin neoplasms. Since most patients present with multiple symptoms of premature aging, Cockayne syndrome can also be considered one of the progeroid disorders. The median age at death described in these patients is 12 years.
How is it treated?
Treatment for Cockayne syndrome is purely symptomatic. The discovery of molecular defects in these disorders has not yet led to specific treatments.