Stefano Crippa


Professor Stefano Crippa is the Medical Director of the Department of Pancreatic Surgery at the IRCCS Ospedale San Raffaele, which is headed by Professor Massimo Falconi, and Associate Professor of General Surgery at the Vita Salute San Raffaele University.

After graduating in Medicine and Surgery in 2003 from the Bicocca University of Milan and specializing in General Surgery in 2009 from the University of Verona, in 2013 he received his PhD in Pancreato-Hepato-Biliary Diseases from the same university. Between 2006 and 2007, he also worked at Massachusetts General Hospital/Harvard Medical School, Boston, USA.

Clinically, Professor Crippa is interested in the treatment of diseases of the pancreas and biliary tract (adenocarcinoma of the pancreas, duodenum and biliary tract, periampullary neoplasms, cystic neoplasms/IPMN, neuroendocrine neoplasms, chronic pancreatitis and gallbladder stones), which he treats with traditional and laparoscopic surgical methods in a multidisciplinary perspective. Other areas of interest are oncological surgery of the digestive system and hernia and adrenal surgery. As the first surgeon, he performed more than 1,200 surgical interventions, including using laparoscopic techniques.

Professor Crippa is mainly engaged in clinical and translational research in the field of pancreatic cancer and pancreatic cystic neoplasms (IPMN) in order to develop innovative therapeutic strategies for the treatment of these diseases.

He is the author and co-author of more than 180 publications in international scientific journals (Hirsch Index 43). He constantly participates in national and international industry congresses. He is also one of the authors of the Italian guidelines for the treatment of acute pancreatitis, cystic lesions of the pancreas and pancreatic cancer.

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Latest publications

Middle pancreatectomy: indications, short- and long-term operative outcomes
Ann Surg. 2007 Jul;246(1):69-76. PubMed PMID: 17592293; PubMed Central PMCID: PMC1899210.
Crippa S, Bassi C, Warshaw AL, Falconi M, Partelli S, Thayer SP, Pederzoli P, Fernández-del Castillo C.
Enucleation of pancreatic neoplasms
Br J Surg. 2007 Oct;94(10):1254-9. PubMed PMID: 17583892.
Crippa S, Bassi C, Salvia R, Falconi M, Butturini G, Pederzoli P.
Branch-duct intraductal papillary mucinous neoplasms: observations in 145 patients who underwent resection
Gastroenterology 2007 Jul;133(1):72-9; quiz 309-10. Epub 2007 May 10. PubMed PMID: 17631133; PubMed Central PMCID: PMC3807096.
Rodriguez JR, Salvia R, Crippa S, Warshaw AL, Bassi C, Falconi M, Thayer SP, Lauwers GY, Capelli P, Mino-Kenudson M, Razo O, McGrath D, Pederzoli P, Fernández-Del Castillo C.
Mucinous cystic neoplasm of the pancreas is not an aggressive entity: lessons from 163 resected patients.
Ann Surg. 2008 Apr;247(4):571-9. doi: 10.1097/SLA.0b013e31811f4449. PubMed PMID: 18362619; PubMed Central PMCID: PMC3806104.
Crippa S, Salvia R, Warshaw AL, Domínguez I, Bassi C, Falconi M, Thayer SP, Zamboni G, Lauwers GY, Mino-Kenudson M, Capelli P, Pederzoli P, Castillo CF.
Mucinproducing neoplasms of the pancreas: an analysis of distinguishing clinical and epidemiologic characteristics
Clin Gastroenterol Hepatol. 2010 Feb;8(2):213-9. doi: 10.1016/j.cgh.2009.10.001. Epub 2009 Oct 14. PubMed PMID: 19835989; PubMed Central PMCID: PMC3135334.
Crippa S, Fernández-Del Castillo C, Salvia R, Finkelstein D, Bassi C, Domínguez I, Muzikansky A, Thayer SP, Falconi M, Mino-Kenudson M, Capelli P, Lauwers GY, Partelli S, Pederzoli P, Warshaw AL.
Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trial
Ann Surg. 2010 Aug;252(2):207-14. doi: 10.1097/SLA.0b013e3181e61e88. PubMed PMID: 20622661.
Bassi C, Molinari E, Malleo G, Crippa S, Butturini G, Salvia R, Talamini G, Pederzoli P.
Surgical management of insulinomas: short- and long-term outcomes after enucleations and pancreatic resections
Arch Surg. 2012 Mar;147(3):261-6. doi: 10.1001/archsurg.2011.1843. PubMed PMID: 22430908 (now JAMA Surgery)
Crippa S, Zerbi A, Boninsegna L, Capitanio V, Partelli S, Balzano G, Pederzoli P, Di Carlo V, Falconi M.
Incidental diagnosis as prognostic factor in different tumor stages of nonfunctioning pancreatic endocrine tumors
Surgery. 2014 Jan;155(1):145-53. doi: 10.1016/j.surg.2013.08.002. PubMed PMID: 24646958.
Crippa S, Partelli S, Zamboni G, Scarpa A, Tamburrino D, Bassi C, Pederzoli P, Falconi M.
Long-term outcomes and prognostic factors in neuroendocrine carcinomas of the pancreas: Morphology matters
Surgery. 2016 Mar;159(3):862-71. doi: 10.1016/j.surg.2015.09.012. PubMed PMID: 26602841.
Crippa S, Partelli S, Bassi C, Berardi R, Capelli P, Scarpa A, Zamboni G, Falconi M.
Low progression of intraductal papillary mucinous neoplasms with worrisome features and high-risk stigmata undergoing non-operative management: a mid-term follow-up analysis
Gut. 2017 Mar;66(3):495-506. doi: 10.1136/gutjnl-2015310162. Epub 2016 Jan 7. PubMed PMID: 26743012.
Crippa S, Bassi C, Salvia R, Malleo G, Marchegiani G, Rebours V, Levy P, Partelli S, Suleiman SL, Banks PA, Ahmed N, Chari ST, Fernández-Del Castillo C, Falconi M.
Justifying vein resection with pancreatoduodenectomy
Lancet Oncol. 2016 May;17(5):e177-8. doi: 10.1016/S1470-2045(16)30037-7. Epub 2016 Apr 27. PubMed PMID: 27301040.
Crippa S, Reni M, Balzano G, Doglioni C, Falconi M.
Is there a role for surgical resection in patients with pancreatic cancer with liver metastases responding to chemotherapy?
Eur J Surg Oncol. 2016 Oct;42(10):1533-9. doi: 10.1016/j.ejso.2016.06.398. Epub 2016 Jun 29. PubMed PMID: 27423449.
Crippa S, Bittoni A, Sebastiani E, Partelli S, Zanon S, Lanese A, Andrikou K, Muffatti F, Balzano G, Reni M, Cascinu S, Falconi M.
Active Surveillance Beyond 5 Years Is Required for Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms Undergoing Non-Operative Management
Am J Gastroenterol. 2017 Jul;112(7):1153-1161. doi: 10.1038/ajg.2017.43. Epub 2017 Feb 28. PubMed PMID: 28244498.
Crippa S, Pezzilli R, Bissolati M, Capurso G, Romano L, Brunori MP, Calculli L, Tamburrino D, Piccioli A, Ruffo G, Fave GD, Falconi M.
Results of First-Round of Surveillance in Individuals at High-Risk of Pancreatic Cancer from the AISP (Italian Association for the Study of the Pancreas) Registry
Am J Gastroenterol. 2019 Apr;114(4):665670. doi: 10.1038/s41395-018-0414-z. PubMed PMID: 30538291.
Paiella S, Capurso G, Cavestro GM, Butturini G, Pezzilli R, Salvia R, Signoretti M, Crippa S, Carrara S, Frigerio I, Bassi C, Falconi M, Iannicelli E, Giardino A, Mannucci A, Laghi A, Laghi L, Frulloni L, Zerbi A.
A multimodality test to guide the management of patients with a pancreatic cyst
Sci Transl Med. 2019 Jul 17;11(501). pii: eaav4772. doi: 10.1126/scitranslmed.aav4772. PubMed PMID: 31316009.
Springer S, Masica DL, Dal Molin M, Douville C, Thoburn CJ, Afsari B, Li L, Cohen JD, Thompson E, Allen PJ, Klimstra DS, Schattner MA, Schmidt CM, Yip-Schneider M, Simpson RE, Fernandez-Del Castillo C, Mino-Kenudson M, Brugge W, Brand RE, Singhi AD, Scarpa A, Lawlor R, Salvia R, Zamboni G, Hong SM, Hwang DW, Jang JY, Kwon W, Swan N, Geoghegan J, Falconi M, Crippa S, Doglioni C, Paulino J, Schulick

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