Renata Clotilde Castellano

Vascular surgeon


Dr. Renata Clotilde Castellano is the coordinator of the Social Welfare Zone in the Vascular Surgery Department of the IRCCS Ospedale San Raffaele under the supervision of Professor Roberto Chiesa.

In 1989 she graduated from the Faculty of Medicine and Surgery of the University of Milan, where in 2002 she received a specialization in vascular surgery. She is also a specialist in general surgery with a specialization in emergency care (specialization of the University of Siena, 1995).

Clinical activities in combination with research activities are focused on all vascular surgery, with a special interest in surgery in the aortic, abdominal and thoracic regions, in diseases affecting the aortic arch, descending thoracic aorta, thoracic and abdominal aorta, atherosclerotic and associated with congenital and acquired abnormalities. She is also engaged in the treatment of lesions of the extracranial carotid arteries, surgical and minimally invasive endovascular treatment. In particular, in the Department of Vascular Surgery, Dr. Castellano is engaged in perioperative planning and clinical management of patients in critical condition.

She is actively engaged in research in the field of aortic pathology, both in the abdominal and thoracic and abdominal divisions, paying special attention to the development of abdominal and thoracic aortic endoprostheses for the treatment of aneurysms and dissections.

Another area of interest is devoted to the pathology of the extracranial carotid artery, she delved into research topics related to indications, diagnostic imaging methods and intra- and postoperative management, in addition to the extended study of plaques. Dr. Castellano is also engaged in minimally invasive endovascular treatment using stents and antiembolic brain protection systems.

She is the author and co-author of 60 publications in industry scientific journals and co-author of 35 book chapters. Her Hirsch Index is 14. Constantly takes part in national and international industry congresses.

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University of Milan
Degree of Doctor of Medicine and Surgery — 1989

University of Siena
Specialization in Emergency Surgery — 1995

University of Milan
Specialization in Vascular Surgery — 2002

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Latest publications

P2X7 receptor antagonism modulates IL-1β and MMP9 in human atherosclerotic vessels.
Sci Rep. 2017 Jul 7;7(1):4872. doi:10.1038/s41598-017-05137-y. PubMed PMID: 28687781; PubMed Central PMCID: PMC5501842.
Lombardi M, Mantione ME, Baccellieri D, Ferrara D, Castellano R, Chiesa R, Alfieri O, Foglieni C.
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A. Endovascular Treatment of Visceral Artery Aneurysms and Pseudoaneurysms in 100 Patients: Covered Stenting vs Transcatheter Embolization.
J Endovasc Ther. 2017 Oct;24(5):709-717. doi: 10.1177/1526602817717715. Epub 2017 Jun 29. PubMed PMID: 28659059.
Venturini M, Marra P, Colombo M, Alparone M, Agostini G, Bertoglio L, Sallemi C, Salvioni M, Gusmini S, Balzano G, Castellano R, Aldrighetti L, Tshomba Y, Falconi M, Melissano G, De Cobelli F, Chiesa R, Del Maschio
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Current results of a combined endovascular and open approach for the treatment of aortoesophageal and aortobronchial fistulae.
Ann Vasc Surg. 2014 Oct;28(7):1782-8. doi: 10.1016/j.avsg.2014.06.003. Epub 2014 Jun 12. PubMed PMID: 24930979.
Kahlberg A, Tshomba Y, Marone EM, Castellano R, Melissano G, Chiesa R.
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P2X7 receptor is expressed in human vessels and might play a role in atherosclerosis.
Int J Cardiol. 2013 Oct 3;168(3):2863-6. doi: 10.1016/j.ijcard.2013.03.084. Epub 2013 Apr 17. PubMed PMID: 23602287.
Piscopiello M, Sessa M, Anzalone N, Castellano R, Maisano F, Ferrero E, Chiesa R, Alfieri O, Comi G, Ferrero ME, Foglieni C.
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Aortobifemoral bypass grafting using expanded polytetrafluoroethylene stretch grafts in patients with occlusive atherosclerotic disease.
Ann Vasc Surg. 2009 Nov-Dec;23(6):764-9. doi: 10.1016/j.avsg.2009.01.004. Epub 2009 Jun 21. PubMed PMID: 19540713
Chiesa R, Marone EM, Tshomba Y, Logaldo D, Castellano R, Melissano G.
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Endovascular abdominal aortic aneurysm repair in a patient with severe hemophilia
B. J Endovasc Ther. 2009 Feb;16(1):120-3. doi: 10.1583/08- 2584.1. PubMed PMID: 19281292.
Marrocco-Trischitta MM, Melissano G, Castellano R, Coppi G, Chiesa R.
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