Patrizia Rovere Querini


Professor Patrizia Rovere Querini is the Director of the Strategic Development Program of the "Integration of Hospital and Territory" project in the Department of Operative General Medicine, Diabetology and Metabolic Endocrine Medicine, which is headed by Professor Emanuele Bosi. She is also an Associate Professor of Internal Medicine at the University of San Raffaele Vita-Salute and Head of the Laboratory of Innate Immunity and Tissue Remodeling at the IRCCS Ospedale San Raffaele.

In 1994, she received the degree of Doctor of Medicine and Surgery from the University of Milan; in 2000 she received the degree of Doctor of Philosophy, awarded in collaboration with the Open University (London) and the Vita-Salute San Raffaele University (Milan). In 2002, she received a specialization in allergology and clinical immunology at the Vita-Salute San Raffaele University.

Professor Rovere Querini is engaged in outpatient activities in the field of internal medicine, clinical immunology, pregnancy immunology and rheumatology. She is the head physician of the outpatient clinic Autoimmunità e Gravidanza, managed in cooperation with the Department of Obstetrics and Gynecology of the Clinica delle Miositi infiammatorie idiopatiche in cooperation with the Department of Neurology. She also collaborates with the Fertility Science Center on the topic of multiple abortions.

Her main research interests concern the role of cell death in the pathogenesis of systemic connectivitis and vasculitis, as well as the role of innate immunity in the mechanisms of tissue damage and repair, with special attention to muscle tissue in idiopathic inflammatory myositis and to the placenta as a target organ in the main complications of pregnancy. She is also interested in the regulation of leukocyte activation in vitro and in vivo, focusing on the molecular pathways that determine the functional capacity and apoptosis susceptibility of human dendritic cells and T-lymphocytes.

She is the author and co-author of 206 publications in industry scientific journals and book chapters. Her Hirsch Index is 55. She constantly participates in national and international industry congresses.

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University of Milan
Degree of Doctor of Medicine and Surgery — 1994

Open University, London
Candidate of Sciences — 2000

Vita Salute San Raffaele University
Specialization in Allergology and Clinical Immunology — 2002

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Latest publications

The immunology of the fetal-placental unit comes of age
Clin Exp Immunol. 2019 Oct;198(1):11-14.
De Lorenzo R, Canti V, Manfredi AA, Rovere-Querini P.
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Safety of fertility treatments in women with systemic autoimmune diseases (SADs).
Expert Opin Drug Saf. 2019 Sep;18(9):841-852.
Vanni VS, De Lorenzo R, Privitera L, Canti V, Viganò P, Rovere-Querini P.
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Exacerbation of Murine Experimental Autoimmune Myositis by Toll-Like Receptor 7/8.
Arthritis Rheumatol. 2018 Aug;70(8):1276-1287.
Sciorati C, Monno A, Doglio MG, Rigamonti E, Ascherman DP, Manfredi AA, Rovere-Querini P
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The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis.
Immunol Rev. 2017 Nov;280(1):112-125.
Erreni M, Manfredi AA, Garlanda C, Mantovani A, Rovere-Querini P
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The clearance of cell remnants and the regeneration of the injured muscle depend on soluble pattern recognition receptor PTX3.
Mol Med. 2017 Jan;22:809-820
Vezzoli M, Sciorati C, Campana L, Monno A, Doglio MG, Rigamonti E, Corna G, Touvier T, Castiglioni A, Capobianco A, Mantovani A, Manfredi AA, Garlanda C, Rovere-Querini P.
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Regulatory T cells and skeletal muscle regeneration.
FEBS J. 2017 Feb;284(4):517-524
Schiaffino S, Pereira MG, Ciciliot S, Rovere-Querini P.
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The Repair of Skeletal Muscle Requires Iron Recycling through Macrophage Ferroportin.
J Immunol. 2016 Sep 1;197(5):1914-25
Corna G, Caserta I, Monno A, Apostoli P, Manfredi AA, Camaschella C, Rovere-Querini P.
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Cell death, clearance and immunity in the skeletal muscle.
Cell Death Differ. 2016 Jun;23(6):927-37
Sciorati C, Rigamonti E, Manfredi AA, Rovere-Querini P
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FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration.
PLoS One. 2015 Jun 3;10(6):e0128094.
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, Almada AE, Mondino A, Wagers AJ, Manfredi AA, Rovere-Querini P.
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Vessel-associated myogenic precursors control macrophage activation and clearance of apoptotic cells.
Clin Exp Immunol. 2015 Jan;179(1):62-7.
Bosurgi L, Brunelli S, Rigamonti E, Monno A, Manfredi AA, Rovere-Querini P.
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Required role of apoptotic myogenic precursors and toll-like receptor stimulation for the establishment of autoimmune myositis in experimental murine models.
Arthritis Rheumatol. 2015 Mar;67(3):809-22.
Sciorati C, Monno A, Ascherman DP, Seletti E, Manfredi AA, Rovere-Querini P.
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Leukocyte HMGB1 is required for vessel remodeling in regenerating muscles.
J Immunol. 2014 Jun 1;192(11):5257-64.
Campana L, Santarella F, Esposito A, Maugeri N, Rigamonti E, Monno A, Canu T, Del Maschio A, Bianchi ME, Manfredi AA, Rovere-Querini P.
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Endometriosis, a disease of the macrophage.
Front Immunol. 2013 Jan 28;4:9.
Capobianco A, Rovere-Querini P.
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