Nicoletta Anzalone



Professor Nicoletta Anzalone heads the Functional Department of Advanced Neurovascular Imaging in the Department of Neuroradiology of the IRCCS Ospedale San Raffaele under the supervision of Professor Andrea Falini. She is Associate Professor of Neuroradiology at Vita-Salute San Raffaele University.

After graduating from the University of Milan in 1985 with a degree in Medicine and Surgery, she received a specialization in neurology and radio diagnostics in 1989 and 1993 at the same institute.

In addition to clinical activities in the field of neuroradiology, Professor Anzalone will conduct clinical research in the field of neurovascular and neuro-oncological medicine. In particular, she is an expert in the field of pathology of cerebral vessels, visualization of walls, brain perfusion and contrast media.

He is the author and co-author of 76 publications in industry scientific journals. Her Hirsch Index is 23.
Constantly takes part in national and international industry congresses.


University of Milan
Degree of Doctor of Medicine and Surgery — 1985

University of Milan
Specialization in Neurology — 1989

University of Milan
Specialization in Radio Diagnostics — 1993

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Latest publications

Comparison of T1 mapping and fixed T1 method for dynamic contrast-enhanced MRI perfusion in brain gliomas.
Eur Radiol. 2019 Jul;29(7):3467-3479. doi: 10.1007/s00330-019-06122-x. Epub 2019 Apr 10. PubMed PMID: 30972545
Conte GM, Altabella L, Castellano A, Cuccarini V, Bizzi A, Grimaldi M, Costa A, Caulo M, Falini A, Anzalone N
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R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma.
Blood. 2019 Jul 18;134(3):252-262.doi: 10.1182/blood.2019000633. Epub 2019 May 22. PubMed PMID: 31118164.
Ferreri AJM, Calimeri T, Conte GM, Cattaneo D, Fallanca F, Ponzoni M, Scarano E, Curnis F, Nonis A, Lopedote P, Citterio G, Politi LS, Foppoli M, Girlanda S, Sassone M, Perrone S, Cecchetti C, Ciceri F, Bordignon C, Corti A, Anzalone N.
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Brain Gliomas: Multicenter Standardized Assessment of Dynamic Contrast-enhanced and Dynamic Susceptibility Contrast MR Images.
Radiology. 2018 Jun;287(3):933-943. doi: 10.1148/radiol.2017170362. Epub 2018 Jan 22. PubMed PMID: 29361245.
Anzalone N, Castellano A, Cadioli M, Conte GM, Cuccarini V, Bizzi A, Grimaldi M, Costa A, Grillea G, Vitali P, Aquino D, Terreni MR, Torri V, Erickson BJ, Caulo M.
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N. Reproducibility of dynamic contrast-enhanced MRI and dynamic susceptibility contrast MRI in the study of brain gliomas: a comparison of data obtained using different commercial software.
Radiol Med. 2017 Apr;122(4):294-302. doi:10.1007/s11547-016-0720-8. Epub 2017 Jan 9. PubMed PMID: 28070841.
Conte GM, Castellano A, Altabella L, Iadanza A, Cadioli M, Falini A, Anzalone
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Dynamic contrastenhanced and dynamic susceptibility contrast perfusion MR imaging for glioma grading: Preliminary comparison of vessel compartment and permeability parameters using hotspot and histogram analysis.
Eur J Radiol. 2016 Jun;85(6):1147-56. doi:10.1016/j.ejrad.2016.03.020. Epub 2016 Mar 22. PubMed PMID: 27161065.
Santarosa C, Castellano A, Conte GM, Cadioli M, Iadanza A, Terreni MR, Franzin A, Bello L, Caulo M, Falini A, Anzalone N.
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Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging.
J Magn Reson Imaging. 2015 Feb;41(2):296-313. doi: 10.1002/jmri.24648. Epub 2014 May 12. Review. PubMed PMID: 24817252.
Shiroishi MS, Castellazzi G, Boxerman JL, D'Amore F, Essig M, Nguyen TB, Provenzale JM, Enterline DS, Anzalone N, Dörfler A, Rovira À, Wintermark M, Law M.
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Comparison of 3D TOF-MRA and 3D CE-MRA at 3T for imaging of intracranial aneurysms.
Eur J Radiol. 2013 Dec;82(12):e853-9. doi: 10.1016/j.ejrad.2013.08.052. Epub 2013 Sep 12. PubMed PMID: 24103356.
Cirillo M, Scomazzoni F, Cirillo L, Cadioli M, Simionato F, Iadanza A, Kirchin M, Righi C, Anzalone N.
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Perfusion MRI: the five most frequently asked clinical questions.
AJR Am J Roentgenol. 2013 Sep;201(3):W495-510. doi: 10.2214/AJR.12.9544. Review.PubMed PMID: 23971482; PubMed Central PMCID: PMC3842445
Essig M, Nguyen TB, Shiroishi MS, Saake M, Provenzale JM, Enterline DS, Anzalone N, Dörfler A, Rovira À, Wintermark M, Law M.
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Optimizing contrast-enhanced magnetic resonance imaging characterization of brain metastases: relevance to stereotactic radiosurgery.
Neurosurgery. 2013 May;72(5):691-701. doi: 10.1227/NEU.0b013e3182889ddf. Review. PubMed PMID: 23381488.
Anzalone N, Essig M, Lee SK, Dörfler A, Ganslandt O, Combs SE, Picozzi P
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Perfusion MRI: the five most frequently asked technical questions. AJR Am J Roentgenol.
2013Jn;200(1):24-34. doi: 10.2214/AJR.12.9543. Review. PubMed PMID: 23255738; PubMed Central PMCID: PMC3593114
Essig M, Shiroishi MS, Nguyen TB, Saake M, Provenzale JM, Enterline D, Anzalone N, Dörfler A, Rovira A, Wintermark M, Law M.
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Cerebral neoplastic enhancing lesions: multicenter, randomized, crossover intraindividual comparison between gadobutrol (1.0M) and gadoterate meglumine (0.5M) at 0.1 mmol Gd/kg body weight in a clinical setting
Eur JRadiol. 2013 Jan;82(1):139-45. doi: 10.1016/j.ejrad.2011.07.005. Epub 2011 Sep 3. PubMed PMID: 21890295.
Anzalone N, Scarabino T, Venturi C, Cristaudo C, Tartaro A, Scotti G, Zimatore D, Floris R, Carriero A, Longo M, Cirillo M, Cova MA, Gatti S, Voth M, Colosimo C
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Follow-up of coiled cerebral aneurysms: comparison of three-dimensional time-of-flight magnetic resonance angiography at 3 tesla with three-dimensional time-of-flight magnetic resonance angiography and contrastenhanced magnetic resonance angiography at 1.5 Tesla.
Aug;43(8):559-67. doi:10.1097/RLI.0b013e31817e9b0b. PubMed PMID: 18648255
Anzalone N, Scomazzoni F, Cirillo M, Cadioli M, Iadanza A, Kirchin MA, Scotti G.
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Carotid artery stenosis: intraindividual correlations of 3D time-of-flight MR angiography, contrast-enhanced MR angiography, conventional DSA, and rotational angiography for detection and grading.
Radiology. 2005 Jul;236(1):204-13. Epub 2005 Jun 13. PubMed PMID:15955853.
Anzalone N, Scomazzoni F, Castellano R, Strada L, Righi C, Politi LS, Kirchin MA, Chiesa R, Scotti G
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