Giulia Martina Cavestro


Professor Giulia Martina Cavestro is a gastroenterologist, Associate Professor of the Department of Gastroenterology and Digestive Endoscopy at the IRCCS Ospedale San Raffaele under the supervision of Professor Pier Alberto Testoni, where she is also responsible for the Functional Department of GASTRO PER ME (gastroenterological personalized medicine).

She is also the Director of the School of Specialization in Diseases of the Digestive System of the Vita-Salute San Raffaele University of Milan and an Associate Professor in Gastroenterology and Digestive Endoscopy at the same university.

After graduating from the University of Padua in Medicine and Surgery in 1996, she specialized in diseases of the digestive system at the University of Parma in 2000. Finally, in 2005, she received a doctorate in Hepato-Digestive Pathophysiology from the University of Parma.

Prof. Cavestro's clinical work focuses in particular on hereditary gastroenterological tumor syndromes within the GASTRO PER ME program dedicated to the care of families with genetic mutations caused by hereditary diseases such as: Lynch syndrome, classic and attenuated familial polyposis, Peutz-Jeghers syndrome and juvenile polyposis, Gardner's syndrome, familial and hereditary pancreatic cancer, and familial and hereditary gastric cancer.

In addition, the professor treats juvenile tumors (<50 years) of the stomach, intestines, and pancreas. Performs daily diagnostic and operative endoscopy of the upper digestive tract (esophagogastroduodenoscopy) and lower (colonoscopy). Finally, the professor carries out outpatient activities in the field of diseases of the digestive system.

In terms of research, Prof. Cavestro is responsible for research activities in the field of hereditary gastroenterological tumor syndromes. In particular, she is the leader of research projects related to: oral and fecal microbiota in Lynch syndrome, exogenous (diet and lifestyle) and endogenous (genetic) risk factors for juvenile colorectal cancer, evaluation of the RABL3 gene in familial pancreatic cancer, and the role endoscopic video capsule for Lynch syndrome. Professor also participates in the European Prospective Registry for Lynch Syndrome (PLSD) and in the Italian Registry of Familial Pancreatic Cancer.

She is the author of more than 80 original scientific articles published in international journals. Her Hirsch Index is 27. She constantly participates as a speaker and moderator at national and international industry conferences.

Read moreRead less

Do you need an appointment?

Contact us and we will take care of you.


Latest publications

Association of Polyps with Early-Onset Colorectal Cancer and Throughout Surveillance: Novel Clinical and Molecular Implications
Cancers. 2019 Nov 29;11(12).
Perea García J, Arribas J, Cañete Á, García JL, Álvaro E, Tapial S, Narváez C, Vivas A, Brandáriz L, Hernández-Villafranca S, Rueda D, Rodríguez Y, Pérez-García J, Olmedillas-López S, García-Olmo D, Cavestro GM, Urioste M, Goel A, González-Sarmiento R.
Colorectal cancer screening from 45 years of age: Thesis, antithesis and synthesis
World J Gastroenterol. 2019 Jun 7;25(21):2565-2580.
Mannucci A, Zuppardo RA, Rosati R, Leo MD, Perea J, Cavestro GM.
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med. 2019Jul 24. doi: 10.1038/s41436-019-0596-9
Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H,
Early-onset colorectal cancer: trends and challenges
Lancet Gastroenterol Hepatol. 2019 Jul;4(7):491-492.
Cavestro GM, Zuppardo RA, Mannucci A.
Results of First-Round of Surveillance in Individuals at High- Risk of Pancreatic Cancer from the AISP (Italian Association for the Study of the Pancreas) Registry
Am J Gastroenterol. 2019;114:665-670.
Paiella S, Capurso G, Cavestro GM, Butturini G, Pezzilli R, Salvia R, Signoretti M, Crippa S, Carrara S, Frigerio I, Bassi C, Falconi M, Iannicelli E, Giardino A, Mannucci A, Laghi A, Laghi L, Frulloni L, Zerbi A.
Early onset sporadic colorectal cancer: Worrisome trends and oncogenic features.
Dig Liver Dis. 2018;50:521-532.
Cavestro GM, Mannucci A, Zuppardo RA, Di Leo M, Stoffel E, Tonon G.
Low Alcohol and Cigarette Use Is Associated to the Risk of Developing Chronic Pancreatitis Pancreas
Di Leo M, Leandro G, Singh SK, Mariani A, Bianco M, Zuppardo RA, Goni E, Rogger TM, Di Mario F, Guslandi M, De Cobelli F, Del Maschio A, Testoni PA, Cavestro GM.
Meta-analysis of the impact of SPINK1 p.N34S gene variation in Caucasic patients with chronic pancreatitis
An update. Dig Liver Dis. 2017;49:847-853.
Di Leo M, Bianco M, Zuppardo RA, Guslandi M, Calabrese F, Mannucci A, Neri TM, Testoni PA, Leandro G, Cavestro GM.
A single-centre prospective, cohort study of the natural history of acute pancreatitis
Dig Liver Dis. 2015;47:205-10.
Cavestro GM, Leandro G, Di Leo M, Zuppardo RA, Morrow OB, Notaristefano C, Rossi G, Testoni SG, Mazzoleni G, Alessandri M, Goni E, Singh SK, Giliberti A, Bianco M, Fanti L, Viale E, Arcidiacono PG, Mariani A, Petrone MC, Testoni PA.
Study design biases in pancreatic inflammatory disease
Gut 2012; 61:1778-9.
Cavestro GM, Mariani A, Singh SK, Arcidiacono PG, Testoni PA.
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis
Am J Gastroenterol 2010;105:199-206.
Cavestro GM, Zuppardo RA, Bertolini S, Sereni G, Frulloni L, Okolicsanyi S, Calzolari C, Singh SK, Sianesi M, Del Rio P, Leandro G, Franzè A, Di Mario F.
Italian Association for the Study of the Pancreas (AISP). Italian consensus guidelines for chronic pancreatitis
Dig Liver Dis. 2010;42:381-406.
Balzano G, Benini L, Calculli L, Campra D, Capurso G, Cavestro GM, De Angelis C, Ghezzo L, Manfredi R, Malesci A, Mariani A, Mutignani M, Ventrucci M, Zamboni G, Amodio A, Vantini I.
Classification of acute pancreatitis- 2012: revision of the Atlanta classification and definitions by international consensus
Gut. 2013;62:102-11.
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group.

Do you need an appointment?

Contact us and we will take care of you.