Giulia Martina Cavestro

个人简介

Giulia Martina Cavestro教授是IRCCS圣拉斐尔科学研究医院胃肠病与消化内镜科的副教授,也是GASTRO PER ME(胃肠病个性化医疗)部门负责人,在Pier Alberto Testoni教授的指导下开展工作。

Cavestro教授也是米兰圣拉斐尔生命健康大学消化系统疾病专业学院院长,还是该校胃肠病与消化内镜科的副教授。

Cavestro教授于1996年毕业于帕多瓦大学的医学院,2000年在帕尔马大学获得消化系统疾病专业学位。2005年,她在帕尔马大学获得肝脏与消化系统病理生理学博士学位。

Cavestro教授的临床工作主要关注GASTRO PER ME项目内的遗传性胃肠肿瘤综合征,致力于护理带有基因突变的遗传病家族,例如:林奇综合征、经典和减毒家族性息肉病、佩吉综合征和幼年性息肉病综合征、加德纳综合征、家族性和遗传性胰腺癌以及家族性和遗传性胃癌。

此外,Cavestro教授还治疗胃、肠和胰腺的幼年型肿瘤(<50岁)。Cavestro教授从事上消化道(食管胃十二指肠镜检查)和下消化道(结肠镜检查)的日常诊断和手术内镜检查。Cavestro教授开展了消化系统疾病领域的门诊活动。

在研究方面,Cavestro教授从事遗传性胃肠道肿瘤综合征领域的研究活动。她领导了和下列课题有关的研究项目:林奇综合征患者的口腔和粪便菌群、幼年结直肠癌的外源性(饮食和生活方式)和内源性(遗传)风险因素、家族性胰腺癌中RABL3基因的评价、胶囊视频内窥镜在林奇综合征中的应用。Cavestro教授还参与了欧洲林奇综合征前瞻性登记研究(PLSD)和意大利家族性胰腺癌登记研究。

Cavestro教授以作者身份在国际学术期刊上发表了80多篇原创科研论文。H指数为27。Ratti医生经常作为发言人和主持人参加意大利国内外行业会议。

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出版物

最新出版物

Association of Polyps with Early-Onset Colorectal Cancer and Throughout Surveillance: Novel Clinical and Molecular Implications
Cancers. 2019 Nov 29;11(12).
Perea García J, Arribas J, Cañete Á, García JL, Álvaro E, Tapial S, Narváez C, Vivas A, Brandáriz L, Hernández-Villafranca S, Rueda D, Rodríguez Y, Pérez-García J, Olmedillas-López S, García-Olmo D, Cavestro GM, Urioste M, Goel A, González-Sarmiento R.
Colorectal cancer screening from 45 years of age: Thesis, antithesis and synthesis
World J Gastroenterol. 2019 Jun 7;25(21):2565-2580.
Mannucci A, Zuppardo RA, Rosati R, Leo MD, Perea J, Cavestro GM.
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med. 2019Jul 24. doi: 10.1038/s41436-019-0596-9
Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H,
Early-onset colorectal cancer: trends and challenges
Lancet Gastroenterol Hepatol. 2019 Jul;4(7):491-492.
Cavestro GM, Zuppardo RA, Mannucci A.
Results of First-Round of Surveillance in Individuals at High- Risk of Pancreatic Cancer from the AISP (Italian Association for the Study of the Pancreas) Registry
Am J Gastroenterol. 2019;114:665-670.
Paiella S, Capurso G, Cavestro GM, Butturini G, Pezzilli R, Salvia R, Signoretti M, Crippa S, Carrara S, Frigerio I, Bassi C, Falconi M, Iannicelli E, Giardino A, Mannucci A, Laghi A, Laghi L, Frulloni L, Zerbi A.
Early onset sporadic colorectal cancer: Worrisome trends and oncogenic features.
Dig Liver Dis. 2018;50:521-532.
Cavestro GM, Mannucci A, Zuppardo RA, Di Leo M, Stoffel E, Tonon G.
Low Alcohol and Cigarette Use Is Associated to the Risk of Developing Chronic Pancreatitis Pancreas
2017;46:225-229.
Di Leo M, Leandro G, Singh SK, Mariani A, Bianco M, Zuppardo RA, Goni E, Rogger TM, Di Mario F, Guslandi M, De Cobelli F, Del Maschio A, Testoni PA, Cavestro GM.
Meta-analysis of the impact of SPINK1 p.N34S gene variation in Caucasic patients with chronic pancreatitis
An update. Dig Liver Dis. 2017;49:847-853.
Di Leo M, Bianco M, Zuppardo RA, Guslandi M, Calabrese F, Mannucci A, Neri TM, Testoni PA, Leandro G, Cavestro GM.
A single-centre prospective, cohort study of the natural history of acute pancreatitis
Dig Liver Dis. 2015;47:205-10.
Cavestro GM, Leandro G, Di Leo M, Zuppardo RA, Morrow OB, Notaristefano C, Rossi G, Testoni SG, Mazzoleni G, Alessandri M, Goni E, Singh SK, Giliberti A, Bianco M, Fanti L, Viale E, Arcidiacono PG, Mariani A, Petrone MC, Testoni PA.
Study design biases in pancreatic inflammatory disease
Gut 2012; 61:1778-9.
Cavestro GM, Mariani A, Singh SK, Arcidiacono PG, Testoni PA.
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis
Am J Gastroenterol 2010;105:199-206.
Cavestro GM, Zuppardo RA, Bertolini S, Sereni G, Frulloni L, Okolicsanyi S, Calzolari C, Singh SK, Sianesi M, Del Rio P, Leandro G, Franzè A, Di Mario F.
Italian Association for the Study of the Pancreas (AISP). Italian consensus guidelines for chronic pancreatitis
Dig Liver Dis. 2010;42:381-406.
Balzano G, Benini L, Calculli L, Campra D, Capurso G, Cavestro GM, De Angelis C, Ghezzo L, Manfredi R, Malesci A, Mariani A, Mutignani M, Ventrucci M, Zamboni G, Amodio A, Vantini I.
Classification of acute pancreatitis- 2012: revision of the Atlanta classification and definitions by international consensus
Gut. 2013;62:102-11.
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group.

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