Giorgia Mangili

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Specialty:

Gynecology Gynecology Obstetrics and Reproductive Medicine Gynecologic Oncology Oncology

Profession:

Gynecologist

Location:

Department of Gyneacology, obstetrics and reproductive medicine @ Ospedale San Raffaele

Languages:

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Biography

Dr. Giorgia Mangili is the Head of the Gynecology Oncology Unit in the Obstetrics and Gynecology Department of IRCCS Ospedale San Raffaele in Milan, under the direction of the Professor Massimo Candiani.

In 1983, she graduated from the Faculty of Medicine and Surgery of the University of Milan. In 1987, she completed specialization there in obstetrics and gynecology, and in 1991 - in oncology. In 2017, she passed state certification for the position of the Ordinary Professor in Obstetrics and Gynecology.

Dr. Mangili’s clinical practice focuses on gynecological oncology, with many years of experience in the treatment of gynecological tumors, tumors during pregnancy and rare tumors affecting the reproductive system, for which the San Raffaele Clinical Institute is a national center of excellence. In addition, she has been involved in fertility preservation of patients with tumors for many years, and is also the head of the Maternity and Tumors department.

Giorgia Mangili is the principal investigator in national and international Phase II and III trials conducted in accordance with the requirements of the GCP (Good Clinical Practice), and her research activities focus on innovative drugs for gynecological oncology and the treatment of rare tumors.

Today she is the author and co-author of chapters in books on gynecological oncology and about 150 articles published in national and international scientific journals. Her Hirsch index is 30. She is the member of many scientific societies, in particular, the European Society of Gynecological Oncology (ESGO), European Organization for the Treatment of Trophoblastic Disease (EOTTD), AIOM.

She is the member of the Board of Directors of the MITO GROUP Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies.

Together with psychologist Valentina Di Mattei, she founded the Salute allo Specchio Onlus in 2013, which aims to support women undergoing cancer treatment at the San Raffale Clinical Institute from a psychological, aesthetic and psychomotor point of view.

Education

University of Milan

Degree in Medicine and Surgery – 1983

University of Milan

Specialization in Obstetrics and Gynecology – 1987

University of Milan

Specialization in Oncology – 1991

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Publications

Today she is the author and co-author of chapters in books on gynecological oncology and about 150 articles published in national and international scientific journals. Her Hirsch index is 30.

Latest publications

Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.

N Engl J Med. 2019 Sep 28

González-Martín A, Pothuri B, Vergote I, DePont Christensen R, Graybill W, Mirza MR, McCormick C, Lorusso D, Hoskins P, Freyer G, Baumann K, Jardon K, Redondo A, Moore RG, Vulsteke C, O'Cearbhaill RE, Lund B, Backes F, Barretina-Ginesta P, Haggerty AF, Rubio-Pérez MJ, Shahin MS, Mangili G, Bradley WH, Bruchim I, Sun K, Malinowska IA, Li Y, Gupta D, Monk BJ; PRIMA/ENGOT-OV26/GOG-3012 Investigators

Management of recurrent ovarian cancer: when platinum-based regimens are not a therapeutic option.

Int J Gynecol Cancer. 2019 Nov;29(9):1431-1436. doi: 10.1136/ijgc-2019-000624. Epub 2019 Sep 18

Bergamini A, Bocciolone L, Fodor A, Candiani M, Mangili G.

A Pictorial Ultrasound Essay of Gestational Trophoblastic Disease.

J Ultrasound Med. 2019 Aug 29

Cavoretto P, Cioffi R, Mangili G, Petrone M, Bergamini A, Rabaiotti E, Valsecchi L, Candiani M, Seckl MJ

Conservative surgery in stage I adult type granulosa cells tumors of the ovary: Results from the MITO-9 study.

Gynecol Oncol. 2019 Aug;154(2):323-327.

Bergamini A, Cormio G, Ferrandina G, Lorusso D, Giorda G, Scarfone G, Bocciolone L, Raspagliesi F, Tateo S, Cassani C, Savarese A, Breda E, De Giorgi U, Mascilini F, Candiani M, Kardhashi A, Biglia N, Perrone AM, Pignata S, Mangili G.

Does methotrexate (MTX) dosing in a 8-day MTX/FA regimen for the treatment of low-risk gestational trophoblastic neoplasia affect outcomes? The MITO-9 study.

Gynecol Oncol. 2018 Dec;151(3):449-452

Mangili G, Cioffi R, Danese S, Frigerio L, Ferrandina G, Cormio G, Rabaiotti E, Scarfone G, Gadducci A, Bergamini A, Pisano C, Candiani M

Laparoscopic surgery in the treatment of stage I adult granulosa cells tumors of the ovary: Results from the MITO-9 study.

Eur J Surg Oncol. 2018

Bergamini A, Ferrandina G, Candiani M, Cormio G, Giorda G, Lauria R, Perrone AM, Scarfone G, Breda E, Savarese A, Frigerio L, Gadducci A, Mascilini F, Maneschi F, Cassani C, Marchetti C, Cecere SC, Biglia N, De Giorgi U, Raspagliesi F, Lorusso D, Mangili G

Reproductive Outcomes After Gestational Trophoblastic Neoplasia. A Comparison Between Single-Agent and Multiagent Chemotherapy: Retrospective Analysis From the MITO-9 Group.

Int J Gynecol Cancer. 2018 Feb;28(2):332-337

Cioffi R, Bergamini A, Gadducci A, Cormio G, Giorgione V, Petrone M, Rabaiotti E, Pella F, Candiani M, Mangili G.

Fertility preservation in women harboring deleterious BRCA mutations: ready for prime time?

Hum Reprod. 2018 Feb 1;33(2):181-187.

Peccatori FA, Mangili G, Bergamini A, Filippi F, Martinelli F, Ferrari F, Noli S, Rabaiotti E, Candiani M, Somigliana E.

Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting.

Eur J Surg Oncol. 2019

Ray-Coquard I, Trama A, Seckl MJ, Fotopoulou C, Pautier P, Pignata S, Kristensen G, Mangili G, Falconer H, Massuger L, Sehouli J, Pujade-Lauraine E, Lorusso D, Amant F, Rokkones E, Vergote I, Ledermann JA RARECARENet Working Group.

Randomized Controlled Trial Testing the Efficacy of Platinum-Free Interval Prolongation in Advanced Ovarian Cancer: The MITO-8, MaNGO, BGOG-Ov1, AGO-Ovar2.16, ENGOT-Ov1, GCIG Study.

J Clin Oncol. 2017 Oct 10;35(29):3347-3353.

Pignata S, Scambia G, Bologna A, Signoriello S, Vergote IB, Wagner U, Lorusso D, Murgia V, Sorio R, Ferrandina G, Sacco C, Cormio G, Breda E, Cinieri S, Natale D, Mangili G, Pisano C, Cecere SC, Di Napoli M, Salutari V, Raspagliesi F, Arenare L, Bergamini A, Bryce J, Daniele G, Piccirillo MC, Gallo C, Perrone F.

Salvage high-dose chemotherapy in female patients with relapsed/refractory germ-cell tumors: a retrospective analysis of the European Group for Blood and Marrow Transplantation (EBMT).

Ann Oncol. 2017 Aug 1;28(8):1910-1916.

De Giorgi U, Richard S, Badoglio M, Kanfer E, Bourrhis JH, Nicolas-Virelizier E, Vettenranta K, Lioure B, Martin S, Dreger P, Schuler MK, Thomson K, Scarpi E, Rosti G, Selle F, Mangili G, Lanza F, Bregni M; Solid Tumours Working Party (STWP) of the EBMT.

Long-acting recombinant follicle-stimulating hormone in random-start ovarian stimulation protocols for fertility preservation in women with cancer.

Acta Obstet Gynecol Scand. 2017 Aug;96(8):949-953

Sarais V, Paffoni A, Pagliardini L, Filippi F, Martinelli F, Mangili G, Candiani M, Papaleo E.

Fertility preservation in women with borderline ovarian tumours.

Cancer Treat Rev. 2016 Sep;49:13-24

Mangili G, Somigliana E, Giorgione V, Martinelli F, Filippi F, Petrella MC, Candiani M, Peccatori F.

The role of staging and adjuvant chemotherapy in stage I Malignant ovarian germ cell tumors (MOGTs): the MITO-9 study.

Ann Oncol. 2017

Mangili G, Sigismondi C, Lorusso D, Cormio G, Candiani M, Scarfone G, Mascilini F, Gadducci A, Mosconi AM, Scollo P, Cassani C, Pignata S, Ferrandina G.

Management of bilateral malignant ovarian germ cell tumors: a MITO-9 retrospective study.

Int J Gynecol Cancer. 2015 Feb;25(2):203-7.

Sigismondi C, Scollo P, Ferrandina G, Candiani M, Angioli R, Viganò R, Scarfone G, Mangili G.

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