Francesco De Cobelli



Professor Francesco De Cobelli is the Head of the Department of Radiology at the Ospedale San Raffaele Clinical Research Institute in Milan, as well as Full professor in Radiology at Vita-Salute San Raffaele University. In addition, he is the Director of the School of Specialization in Radiology, Co-Director of the International PhD Doctorate in Clinical and Experimental Medicine at Vita-Salute San Raffaele University and part of Research Units in Clinical and Experimental Radiology at the Center for Experimental Imaging at San Raffaele Clinical Research Institute.

He graduated from the Faculty of Medicine and Surgery of the University of Milan in 1991. During this period, he also studied as a fellow in the United States at Case Western Reserve University in Cleveland, USA. He specialized in Radiology at the University of Milan in 1995 and began his clinical career in San Raffaele in 1996 at the Radiology Department where he later became the Unit Head of the Magnetic Resonance service while receiving his nomination as Professor, first adjunct and then full. As of 2014, he is the Director of the Post-graduate School in radiology (specialization) and Co-Director of the International PhD course in Clinical and Experimental Medicine at Università Vita-Salute San Raffaele, and as of 2019 President of the bachelor’s degree in nursing. As of the same year, he is Director of the Radiology Department of Ospedale San Raffaele Clinical Research Institute. 

Professor De Cobelli’s main areas of clinical and research include magnetic resonance imaging, abdominaland pelvic radiology (in particular hepatobiliary and pancreatic tumors, tumors of the stomach and esophagus, colon and rectum cancers and renal and prostate malignancies), cardiac imaging and interventional radiology in oncology (Interventional Oncology). His scientific research is mainly focused on detection and characterization of oncological imaging and the use of imaging as a non-invasive biomarker for the evaluation of treatment response and has been involved in the validation of radiomic algorithms as add-on quantitative tools in aiding diagnosis and describing diseases He is currently the principal investigator and co- investigator in numerous national and international clinical trials.

Professor Francesco De Cobelli is author of 395 scientific articles published in national and international journals with an H index (Scopus) of 55 and 14,193 citations (Google Scholar: 63 index and 17,167cit). He is invited speaker in national and international meetings, and scientific member in International symposia. According to a recent adjournment published by PLOS Biology in 2023, has been ranked in the top 2% of Top Scientists worldwide in their research field (Imaging).

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University of Milan

Degree in Medicine and Surgery – 1991

University of Milan

Radiology Specialization – 1995

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Being the author of 212 scientific articles published in national and international journals, books on magnetic resonance imaging and more than 30 chapters in other books, Professor Francesco De Cobelli is among the people with high H index and citations (Scopus source: 38 and 5668; Google Scholar source: 45 and 7606).

Latest publications

Apparent diffusion coefficient modifications in assessing gastro-oesophageal cancer response to neoadjuvant treatment: Comparison with tumour regression grade at histology
Eur Radiol.2013;23:2165–74.31.
De Cobelli F, Giganti F, Orsenigo E, Cellina M, Esposito A, Agostini G, Albarello L, Mazza E, Ambrosi A, Socci C, Staudacher C, Del Maschio A.
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Italian registry of cardiac magnetic resonance
Eur J Radiol.2014 Jan;83(1):e15-22.
Francone M, Di Cesare E, Cademartiri F, Pontone G, Lovato L, Matta G, Secchi F, Maffei E, Pradella S, Carbone I, Marano R, Bacigalupo L, Chiodi E, Donato R, Sbarbati S, De Cobelli F, di Renzi P,CMR Italian Registry Group, Ligabue G,Mancini A, Palmierir F, Restaino G, Puppini G, Centonze M, Toscano W, Tessa C, Faletti R, Conti M, Scardapane A, Galea S, Liguori C, Pagliacci M, Lumia D, di Girolamo M
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Apparent Diffusion Coefficient Value and Ratio as Noninvasive Potential Biomarkers to Predict Prostate Cancer Grading: Comparison With Prostate Biopsy and Radical Prostatectomy Specimen.
AJR Am J Roentgenol 2015 Mar;204(3):550-7.
De Cobelli F, Ravelli S, Esposito A, Giganti A, Gallina A, Montorsi F, Del Maschio A.
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Prognostic role of Diffusion-Weighted Magnetic Resonance for resectable gastric cancer.
Radiology 2015 Aug;276(2):444-52.
Giganti F, Orsenigo E, Esposito A, Chiari D, Salerno A, Ambrosi A, Albarello L, Mazza E, Staudacher C, Del Maschio A, De Cobelli F.
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Microwave ablation of liver malignancies: comparison of effects and early outcomes of percutaneous and intraoperative approaches with different liver conditions : New advances in interventional oncology: state of the art.
Med Oncol. 2017 Apr;34(4):49.
De Cobelli F, Marra P, Ratti F, Ambrosi A, Colombo M, Damascelli A, Sallemi C, Gusmini S, Salvioni M, Diana P, Cipriani F, Venturini M, Aldrighetti L, Del Maschio A.
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Therapeutic EUS: Biliary drainage - The interventional radiologist's perspective.
Endosc Ultrasound. 2017 Dec;6:S127-S131
De Cobelli F, Marra P, Diana P, Brembilla G, Venturini M
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Preoperative multiparametric MRI of the prostate for the prediction of lymph node metastases in prostate cancer patients treated with extended pelvic lymph node dissection.
Eur Radiol. 2018 May;28(5):1969-1976.
Brembilla G, Dell'Oglio P, Stabile A, Ambrosi A, Cristel G, Brunetti L, Damascelli A, Freschi M, Esposito A, Briganti A, Montorsi F, Del Maschio A, De Cobelli F.
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PRECISION Study Group Collaborators. MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis
N Engl J Med. 2018 May 10;378(19):1767-1777.
Kasivisvanathan V, Rannikko AS, Borghi M, et al.
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Could perfusion heterogeneity at dynamic contrast-enhanced MRI be used to predict rectal cancer sensitivity to chemoradiotherapy?
Clin. Radiol. 2018 Oct;73(10):911.e1-911.e7
Palmisano A, Esposito A, Rancoita PMV, Di Chiara A, Passoni P, Slim N, Campolongo M, Albarello L, Fiorino C, Rosati R, Del Maschio A, De Cobelli F.
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Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group
Int J Hyperthermia. 2019;36(1):376-382. doi: 10.1080/02656736.2019.1575482. Epub 2019 Mar 26.
Papini E, Pacella CM, Solbiati LA, Achille G, Barbaro D, Bernardi S, Cantisani V, Cesareo R, Chiti A, Cozzaglio L, Crescenzi A, De Cobelli F, Deandrea M, Fugazzola L, Gambelunghe G, Garberoglio R, Giugliano G, Luzi L, Negro R, Persani L, Raggiunti B, Sardanelli F, Seregni E, Sollini M, Spiezia S, Stacul F, Van Doorne D, Sconfienza LM, Mauri G.
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Ct radiomic features of pancreatic neuroendocrine neoplasms (panNEN) are robust against delineation uncertainty
Phys Med. 2019 Jan;57:41-46. doi: 10.1016/j.ejmp.2018.12.005. Epub 2018 Dec 18.
Fiorino C, De Cobelli F.
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Percutaneous ablation techniques for renal cell carcinoma: current status and future trends.
Int. J Hyperthermia. 2019 Oct;36(2):21-30.
Filippiadis DK, Mauri G, Marra P, Haralabopoulos G, Genaro N, De Cobelli F.
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Can DCE-MRI reduce the number of PI-RADS v.2 false positive findings? Role of quantitative pharmacokinetic parameters in prostate lesions characterization.
Eur J Radiol. 2019 Sep;118:51-57
Cristel G, Esposito A, Damascelli A, Briganti A, Ambrosi A, Brembilla G, Brunetti L, Antunes S, Freschi M, Montorsi F, Del Maschio A, De Cobelli F
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Esophagus and stomach: is there a role for MRI?
Magn Reson Imaging Clin N Am. 2020 Feb;28(1):1-15.
De Cobelli F, Palumbo D, Albarello L, Rosati R and Giganti F
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Percutaneous Microwave Ablation Versus Cryoablation in the Treatment of T1a Renal Tumors
Cardiovasc Intervent. Radiol. 2020 Jan;43(1):76-83.
De Cobelli F, Papa M, Panzeri M, Colombo M, Steidler S, Ambrosi A, Cao R, Gusmini S, Marra P, Capitanio U, Bertini R, Venturini M, Losa A, Gaboardi F, Montorsi F, Cardone G.
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