Which are the symptoms?
Clinical manifestations are very diverse and include damage to organs, especially kidney, heart, liver, skin, gastrointestinal tract, nervous system, endocrine system, joints and lungs.
How is it diagnosed?
Diagnosis is usually made by biopsy with appropriate staining. If confirmed, it will be necessary to clarify which proteins are involved in immunocytochemical studies and any genetic studies.
How is it treated?
Different treatments are provided for each form. AL amyloidosis is treated in the same way as multiple myeloma. In AA amyloidosis, treatment of the forms of chronic inflammation that causes it can help. Colchicine is useful in forms associated with familial Mediterranean fever. In other forms, treatment is very varied, and many experiments in this direction are currently being carried out.