Rossana Caldara

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Specialty:

Diabetes (Adults) Transplant Medicine

Profession:

Endocrinologist

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Biography

Dr. Rossana Caldara is an endocrinologist specialized in diabetes and metabolic diseases. She is the Head of the Transplant Medicine program within the Regenerative Medicine and Transplant Unit, led by Professor Lorenzo Piemonti.

Dr. Caldara graduated with honors in Medicine and Surgery from the University of Milan in 1987. In 1992, she completed her specialization in Diabetes and Metabolic Diseases.

Her training includes prestigious fellowships:

1989-1990: Fellowship in Transplant Medicine and Clinical Immunology, Urology and Transplant Surgery at Hôpital Édouard Herriot in Lyon, France.
1992-1993: Postdoctoral Fellowship in Diabetology and Metabolic Diseases at the San Raffaele Scientific Institute.

As the Head of the Transplant Medicine program, Dr. Caldara is responsible for the care, information, and treatment of patients requiring internal medicine expertise, as well as those undergoing kidney, kidney/pancreas, and pancreatic islet transplants. She oversees the patient's entire care pathway, from admission to discharge.

In addition to her ward duties, she conducts regular outpatient clinics and works closely with colleagues in the unit on on-call duties for urgent clinical care, both internally and externally, for transplant patients.

Dr. Caldara is also deeply involved in research activities following GCP (Good Clinical Practice) standards, managing treatment strategies and research protocols. She collaborates with the unit director on managerial and organizational tasks and maintains connections with pharmaceutical companies and internal and external services, including the North Italy Transplant program and the National Transplant Center.

Since 2018, Dr. Caldara has been the Coordinator for Phase 1 clinical trials.

Academically, she is committed to her role as a university tutor at Vita-Salute San Raffaele University and is actively involved in national and international transplant-related engagements.

Dr. Caldara is a member of the Italian Society of Diabetology (SID), the Italian Society of Nephrology (SIN), the Italian Society for Organ Transplantation (SITO), and served on the Operational Committee of the SIN-SITO College for the 2020-2023 term.

Education

State University of Milan
Degree in Medicine and Surgery - 1987

State University of Milan
Specialization in Diabetes and Metabolic Diseases - 1992

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Publications

Latest publications

Kidney-pancreas transplantation is associated with near-normal sexual function in uremic type 1 diabetic patients.

Transplantation. 2011 Oct 15;92(7):802-8.

Salonia A, D'Addio F, Gremizzi C, Briganti A, Dehò F, Caldara R, Orsenigo E, Staudacher C, Socci C, Rigatti P, Secchi A, Montorsi F, Fiorina P.

Near normalization of metabolic and functional features of the central nervous system in type 1 diabetic patients with end-stage renal disease after kidney-pancreas transplantation.

Diabetes Care. 2012 Feb;35(2):367-74.

Fiorina P, Vezzulli P, Bassi R, Gremizzi C, Falautano M, D'Addio F, Vergani A, Chabtini L, Altamura E, Mello A, Caldara R, Scavini M, Magnani G, Falini A, Secchi A.

31P-magnetic resonance spectroscopy (31P-MRS) detects early changes in kidney high-energy phosphate metabolism during a 6-month Valsartan treatment in diabetic and non-diabetic kidney-transplanted patients.

Acta Diabetol. 2012 Dec;49 Suppl 1:S133-9.

Fiorina P, Bassi R, Gremizzi C, Vergani A, Caldara R, Mello A, Del Maschio A, De Cobelli F, Perseghin G, Secchi A.

Renal artery stenosis due to fi bromuscular dysplasia in a transplanted kidney from a deceased donor: a diffi cult diagnosis at color Doppler ultrasonography.

J Clin Ultrasound. 2014 Feb;42(2):116-20.

Venturini M, Querques G, Margari S, Agostini G, Colombo M, Caldara R, Socci C, De Cobelli F, Del Maschio A.

Generation of Donor-specifi c T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation.

Transplantation. 2015 Aug;99(8):1582-9. doi: 10.1097/TP.0000000000000751. PMID: 25989499

Petrelli A, Tresoldi E, Mfarrej BG, Paganelli A, Spotti D, Caldara R, Secchi A, Battaglia M.

Generation of donor-specifi c Tr1 cells to be used after kidney transplantation and defi nition of the timing of their in vivo infusion in the presence of immunosuppression.

J Transl Med. 2017 Feb 21;15(1):40. doi: 10.1186/s12967-017-1133-8.

Mfarrej B, Tresoldi E, Stabilini A, Paganelli A, Caldara R, Secchi A, Battaglia M.

IL28B rs12979860 genotype as a predictor marker of progression to BKVirus Associated nephropathy, after kidney transplantation.

Sci Rep. 2017 Jul 27;7(1):6746. doi: 10.1038/s41598-017-06915-.

Dvir R, Paloschi V, Canducci F, Dell'Antonio G, Racca S, Caldara R, Pantaleo G, Clementi M, Secchi A.

Insulin-mimetic eff ects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation.

Acta Diabetol. 2018 Jul;55(7):715-722. doi: 10.1007/s00592-018-1141-z. Epub 2018 Apr 13. PMID: 29654388

Benedini S, Ermetici F, Briganti S, Codella R, Terruzzi I, Maffi P, Caldara R, Secchi A, Nano R, Piemonti L, Alejandro R, Ricordi C, Luzi L.

Renal Resistance Trend During Hypothermic Machine Perfusion Is More Predictive of Postoperative Outcome Than Biopsy Score: Preliminary Experience in 35 Consecutive Kidney Transplantations.

Artif Organs. 2018 Mar 30. doi: 10.1111/aor.13117. PMID: 29602202

Bissolati M, Gazzetta PG, Caldara R, Guarneri G, Adamenko O, Giannone F, Mazza M, Maggi G, Tomanin D, Rosati R, Secchi A, Socci C.

Everolimus in kidney transplant recipients at high cardiovascular risk: a narrative review.

J Nephrol. 2020 Feb;33(1):69-82. doi: 10.1007/s40620-019-00609-y. PMID: 31028549

Paoletti E, Citterio F, Corsini A, Potena L, Rigotti P, Sandrini S, Bussalino E, Stallone G; ENTROPIA Project.

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. PMID: 32446407

Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheff old A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK.

COVID-19 and kidney transplantation: an Italian Survey and Consensus.

J Nephrol. 2020 Aug;33(4):667-680. doi: 10.1007/s40620-020-00755-8. Epub 2020 Jun 3. PMID: 32495231

Vistoli F, Furian L, Maggiore U, Caldara R, Cantaluppi V, Ferraresso M, Zaza G, Cardillo M, Biancofi ore G, Menichetti F, Russo A, Turillazzi E, Di Paolo M, Grandaliano G, Boggi U; Italian National Kidney Transplantation Network; the Joint Committee of the Italian Society of Organ Transplantation and the Italian Society of Nephrology.

Management of metabolic alterations in adult kidney transplant recipients: A joint position statement of the Italian Society of Nephrology (SIN), the Italian Society for Organ Transplantation (SITO) and the Italian Diabetes Society (SID).

Nutr Metab Cardiovasc Dis. 2020 Aug 28;30(9):1427-1441. doi: 10.1016/j.numecd.2020.05.004. Epub 2020 May 21. PMID: 32605884

Conte C, Maggiore U, Cappelli G, Ietto G, Lai Q, Salis P, Marchetti P, Piemonti L, Secchi A, Capocasale E, Caldara R.

Pregnancy after pancreas-kidney transplantation.

J Nephrol. 2020 Oct;33(5):1009-1018. doi: 10.1007/s40620-020-00860-8. Epub 2020 Sep 21. PMID: 32959341

Caretto A, Caldara R, Castiglioni MT, Scavini M, Secchi A.

Supporting physicians in the management of metabolic alterations in adult kidney transplant recipients: a comment on the joint position statement of the Italian Society of Nephrology (SIN), the Italian Society for Organ Transplantation (SITO) and the Italian Diabetes Society (SID).

J Nephrol. 2020 Oct;33(5):887-893. doi: 10.1007/s40620-020-00839-5.PMID: 32876937

Conte C, Maggiore U, Cappelli G, Ietto G, Lai Q, Salis P, Marchetti P, Piemonti L, Secchi A, Capocasale E, Caldara R

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