Pietro Mortini



Professor Pietro Mortini is the Head of the Neurosurgery and Stereotactic Radiosurgery Unit at IRCCS Ospedale San Raffaele Hospital in Milan and performs outpatient activities at Casa di Cura La Madonnina.

He is Professor of Neurosurgery at the University Vita-Salute San Raffaele and Clinical Professor of Neurological Surgery at George Washington University in Washington D.C. (USA)

His educational pathway began in Parma where he graduated in Medicine and Surgery with honors in 1986. In 1991, he specialized in Neurosurgery at the University of Verona. He gained vast experiences abroad: he attended, among others, the Western General Hospital in Edinburgh, the University of Virginia in Charlottesville and the Hôpital Lariboisière in Paris.

In 1999, he obtained an International Fellowship at the Neurological Institute of the George Washington University which, in 2002, awarded him the title of Visiting Professor of Neurosurgery.

As a surgeon, Prof. Mortini has focused on skull base surgery, brain and spinal tumors and treatment of cerebrovascular pathologies. He has performed more than 8,000 neurosurgical interventions and stereotactic radiosurgery procedures using Gamma Knife.

The Neurosurgery Unit headed by him is an international reference center for the treatment of pituitary tumors (non-secreting Pituitary Adenomas, Cushing's Disease, Acromegaly, Prolactinomas, Craniopharyngiomas), with over 200 cases treated per year. The Unit is at the forefront in the use of new technologies (examples are: three-dimensional intraoperative endoscopy, cortical mapping with intraoperative monitoring, intraoperative ultrasound, intraoperative neurophysiology, minimally invasive cerebral portal surgery and spinal surgery, and neuronavigator). Moreover, the world's first robotic brain tumor removal surgery was performed in the Unit in 2020.

Throughout his career, in addition to his clinical activity, Professor Mortini has dedicated himself to the research and development of new neurosurgical techniques, including the design of over 60 new micro-neurosurgical instruments. Since 2008, he is Director of the School of Specialization in Neurosurgery of the University Vita Salute San Raffaele and Director of various Master degree programs of the same University.

He is the author of over 230 publications published in scientific journals of high international relevance, and is a member of the Editorial Board of several specialized journals. Since 2015, he is Visiting Consultant at Ibn Sina Hospital in Kuwait City.

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University of Parma

Degree in Medicine and Surgery – 1986

University of Verona

Specialization in Neurosurgery – 1989

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Latest publications

The emerging role of gamma knife radiosurgery in the management of glossopharyngeal neuralgia
Neurosurgical Review 2019, 42(1), pp. 31-38
Spina, A., Boari, N., Gagliardi, F., Iannaccone, S., Mortini, P.
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Intrathecal rituximab for IgG 4 -related hypertrophic pachymeningitis
Journal of Neurology, Neurosurgery and Psychiatry 2018. 89(4), pp. 441-444
Della-Torre, E., Campochiaro, C., Cassione, E.B., Acerno, S., Dagna, L.
Fronto-orbitozygomatic approach: Functional and cosmetic outcomes in a series of 169 patients
Journal of Neurosurgery 128(2), 2018. pp. 466-474.
Boari, N., Spina, A., Giudice, L., Bailo, M., Mortini P.
Effectiveness of Gamma Knife Radiosurgery in Improving Psychophysical Performance and Patient's Quality of Life in Idiopathic Trigeminal Neuralgia
World Neurosurgery 110, 2018. pp. e776-e785.
Gagliardi, F., Spina, A., Bailo, M., Bolognesi, A., Mortini P.
Microsurgical therapy of pituitary adenomas
Endocrine 2018 59(1), pp. 72-81.
Mortini P., Barzaghi, L.R., Albano, L., Panni, P., Losa, M.
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Bilateral Temporal Myofascial Flap for the Reconstruction of Frontal Sinus Defects.
World Neurosurgery, 2017. Vol 107. Pp. 477-481.
Gagliardi, F., Bailo, M., Spina, A., Caputy, A.J., Mortini, P.
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Management of endocrine disease risk of overtreatment in patients with adrenal insufficiency: Current and emerging aspects
European Journal of Endocrinology, 2017. Vol 177. Pp. R231-R248.
Mazziotti, G., Formenti, A.M., Frara, S., Roca, E., Mortini, P., Berruti, A., Giustina, A.
Treatment of empty sella associated with visual impairment: a systematic review of chiasmapexy techniques
Pituitary, 2017. Pp. 1-9.
Barzaghi, L.R., Donofrio, C.A., Panni, P., Losa, M., Mortini, P.
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Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement
Pituitary, 2017. Pp. 489-498.
Casanueva, F.F., Barkan, A.L., Buchfelder, M., Klibanski, A., Laws, E.R., Loeffler, J.S., Melmed, S., Mortini, P., Wass, J., Giustina, A. On behalf of The Pituitary Society, Expert Group on Pituitary Tumor.
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Weight gain after subthalamic nucleus deep brain stimulation in Parkinson’s disease is influenced by dyskinesias’ reduction and electrodes’ position
Neurological Sciences, 2017. Pp. 1-7
Balestrino R, Baroncini D, Fichera M, Donofrio C.A, Franzin A, Mortini P, Comi G, Volontè M.A

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