Paolo Cavoretto


Dr. Paolo Ivo Cavoretto is an obstetrician-gynecologist in the Department of Gynecology and Obstetrics at the IRCCS Ospedale San Raffaele under the supervision of Professor Massimo Candiani.

After graduating with honors from the Faculty of Medicine and Surgery of the University of Milan in 1999, he specialized in gynecology and obstetrics at the Vita Salute San Raffaele University of Milan in 2005. In the period from 2004 to 2006, he was awarded a research scholarship at King's College Hospital (London, UK), and in 2006 he received a diploma in fetal medicine at the Fetal Medicine Foundation UK (FMF; London, UK). Since 2006, he has been a lecturer and certified specialist in obstetric ultrasound at the FMF and the Italian Society of Obstetric and Gynecological Ultrasound (SIEOG). Since 2008, he has been collaborating as a teacher and mentor at the courses of medicine and surgery and at the Specialized School of Obstetrics and Gynecology of the Vita-Salute San Raffaele University. In 2011, he received the doctorate in Development of Prenatal Diagnosis and Fetal Therapy from the University of Milan. In 2017, he received a national scientific qualification as a second-level university professor.

Clinically, he practices as a specialist in the maternity ward and delivery rooms, and as co-director of the Fetal Medicine Center as an expert in ultrasound diagnostics, prenatal screening and maternal and fetal medicine. His clinical interest is mainly in high-risk pregnancy, diagnosis, and treatment of structural or genetic fetal abnormalities, fetal echocardiography and neurosonology, intranatal monitoring, ultrasound-guided invasive procedures (for diagnostic/therapeutic purposes) and fetal surgery, in particular for spina bifida.

As for research activities, he is responsible for numerous monocentric or multicenter projects in cooperation with recognized national and international institutions. The main areas of research relate to the diagnosis and treatment of anomalies in the structure of the fetus (especially congenital heart defects) during pregnancy and in the perinatal period; intrauterine treatment for fetal spina bifida and study of the development of the nervous system of affected fetuses; viral cytomegalovirus infections during pregnancy; prediction and prevention of preterm birth using functional magnetic resonance and fetal-placental ultrasound; study of placental and cardiovascular function in pregnant women with pathology, placental insufficiency or conception after IVF / ICSI and egg donation; study of the genetics of IVF/ICSI pregnancies after pre-implantation diagnosis; prediction and monitoring of the state of the fetus and intranatal complications using biophysical techniques and biomarkers.

Finally, Dr. Cavoretto is an active member of the editorial board of the prestigious scientific journal Ultrasound in Obstetrics and Gynecology (ISUOG), the International Fetoscopy Group and the First Quarter and Non-Invasive Genetic Testing Committee (SIEOG) and is already an ISUOG consultant. He works as an associate editor for the scientific journal BMC Pregnancy and Childbirthand as a guest editor for the scientific journal Diagnostics. He is the author and co-author of numerous publications in reputable indexed scientific journals, cooperates at the editorial level and as a reviewer with many other important international periodicals. He constantly participates as a speaker at national and international industry congresses. His Hirsch Index is 15.

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Latest publications

Longitudinal cohort study of uterine artery Doppler in singleton pregnancies obtained by IVF/ICSI with fresh or frozen blastocyst transfers in relation to pregnancy outcomes.
Ultrasound Obstet Gynecol. 2020 Jan 7. doi: 10.1002/uog.21969. [Epub ahead of print] PubMed PMID: 31909549.
Cavoretto P, Farina A, Gaeta G, Sigismondi C, Spinillo S, Casiero D, Pozzoni M, Vigano P, Papaleo E, Candiani M.
A Pictorial Ultrasound Essay of Gestational Trophoblastic Disease
J Ultrasound Med. 2020 Mar;39(3):597-613. doi: 10.1002/jum.15119. Epub 2019 Aug 29. Review. PubMed PMID: 31468566.
Cavoretto P, Cioffi R, Mangili G, Petrone M, Bergamini A, Rabaiotti E, Valsecchi L, Candiani M, Seckl MJ.
Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF/ICSI treatment: meta-analysis of cohort studies.
Ultrasound Obstet Gynecol. 2018 Jan;51(1):43-53. doi: 10.1002/uog.18930. Review. PubMed PMID: 29114987.
Cavoretto P, Candiani M, Giorgione V, Inversetti A, Abu-Saba MM, Tiberio F, Sigismondi C, Farina A
Nuchal translucency measurement, free β-hCG and PAPP-A concentrations in IVF/ICSI pregnancies: systematic review and meta-analysis.
Prenat Diagn. 2017 Jun;37(6):540-555. doi: 10.1002/pd.5052. Epub 2017 May 29. Review. PubMed PMID: 28419502.
Cavoretto P, Giorgione V, Cipriani S, Viganò P, Candiani M, Inversetti A, Ricci E, Parazzini F.
First trimester combined screening test in pregnancies derived from blastocyst transfer.
Eur J Obstet Gynecol Reprod Biol. 2016 Mar;198:50-55. doi: 10.1016/j.ejogrb.2015.12.026. Epub 2015 Dec 31. PubMed PMID: 26785129.
Cavoretto P, Dallagiovanna C, Viganò P, Somigliana E, Persico N, Papaleo E, Faulisi S, Candiani M.
Percutaneous transvesical chorionic villus sampling: a safe alternative method for difficult procedures?
Ultrasound Obstet Gynecol. 2014 Jul;44(1):115-6. doi: 10.1002/uog.13307. Epub 2014 May 29. PubMed PMID: 24452832
Cavoretto P, Dallagiovanna C, Spagnolo D, Candiani M.
Prediction of pulmonary hypoplasia in mid-trimester preterm prelabor rupture of membranes: research or clinical practice?
Ultrasound Obstet Gynecol. 2012 May;39(5):489-94. doi: 10.1002/uog.11172. Review. PubMed PMID: 22539491.
Cavoretto P.
Aberrant right subclavian artery in fetuses with Down syndrome: a systematic review and meta-analysis.
Ultrasound Obstet Gynecol. 2015 Sep;46(3):266-76. doi: 10.1002/uog.14774. Epub 2015 Aug 6. Review. PubMed PMID: 25586729.
Scala C, Leone Roberti Maggiore U, Candiani M, Venturini PL, Ferrero S, Greco T, Cavoretto P.
Congenital heart defects in IVF/ICSI pregnancy: systematic review and meta-analysis.
Ultrasound Obstet Gynecol. 2018 Jan;51(1):33-42. doi: 10.1002/uog.18932. Review. PubMed PMID: 29164811.
Giorgione V, Parazzini F, Fesslova V, Cipriani S, Candiani M, Inversetti A, Sigismondi C, Tiberio F, Cavoretto P.
Prenatal diagnosis and outcome of echogenic fetal lung lesions.
Ultrasound Obstet Gynecol. 2008 Nov;32(6):769-83. doi: 10.1002/uog.6218. Review. PubMed PMID: 18956429.
Cavoretto P, Molina F, Poggi S, Davenport M, Nicolaides KH.
Clinical presentation of hydatidiform mole in northern Italy: has it changed in the last 20 years?
Am J Obstet Gynecol. 2008 Mar;198(3):302.e1-4. doi: 10.1016/j.ajog.2007.09.036. Epub 2008 Feb 21. Review. PubMed PMID: 18177836.
Mangili G, Garavaglia E, Cavoretto P, Gentile C, Scarfone G, Rabaiotti E.
Aberrant right subclavian artery at 11 + 0 to 13 + 6 weeks of gestation in chromosomally normal and abnormal fetuses.
Ultrasound Obstet Gynecol. 2008 Jan;31(1):20-4. PubMed PMID: 18157795.
Borenstein M, Cavoretto P, Allan L, Huggon I, Nicolaides KH.
Lung and heart volumes by three-dimensional ultrasound in normal fetuses at 12-32 weeks' gestation.
Ultrasound Obstet Gynecol. 2006 Feb;27(2):128-33. PubMed PMID:
Peralta CF, Cavoretto P, Csapo B, Falcon O, Nicolaides KH.
Ultrasound Obstet Gynecol. 2006 Feb;27(2):128-33. PubMed PMID:
Ultrasound Obstet Gynecol. 2005 Dec;26(7):718-24. PubMed PMID: 16308896.
Peralta CF, Cavoretto P, Csapo B, Vandecruys H, Nicolaides KH.
Fetal head-to-trunk volume ratio in chromosomally abnormal fetuses at 11 + 0 to 13 + 6 weeks of gestation.
Ultrasound Obstet Gynecol. 2005 Dec;26(7):755-60. PubMed PMID: 16163740.
Falcon O, Cavoretto P, Peralta CF, Csapo B, Nicolaides KH.

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