Mariateresa Castiglioni


Mariateresa Castiglioni is responsible for the Functional Department of Pregnancy Pathology in the Department of Operative Obstetrics and Gynecology at the IRCCS Ospedale San Raffaele under the supervision of Professor Massimo Candiani.

After graduating from the Faculty of Medicine and Surgery of the University of Milan in 1985, she received a specialization at the same institute.

Through close collaboration with the institute's dialectologists, she is mainly involved in the study of diabetes both before pregnancy and during pregnancy. She is also interested in studying women with rheumatic pathology or with abortion problems, late abortion or thrombophilia; and patients with heart disease or endocrinological disorders, including patients with adrenal-genital syndrome.

From a research point of view, Dr. Castiglioni is an expert on markers of cellular and systemic inflammation in patients with multiple abortions and/or antiphospholipid antibody syndrome, studying the effectiveness of treatment with low molecular weight heparin in such patients. As part of the study of the causes of multiple abortions, she was engaged in the study of factors associated with pregnancy implantation anomalies, including genetic variations of the HLA-G system. She has also participated in clinical studies of patients with diabetes, both in relation to preeclampsia in patients with type 1 diabetes, and in regional population-based screening studies for gestational diabetes in Lombardy.

Dr. Castiglioni is the author and co-author of more than 50 scientific articles published in national and international journals. She has published a manual on obstetrics and gynecology addressed to doctors and midwives, which has now reached the fourth edition, and has also participated, with her chapters in the publication of other didactic texts.

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University of Milan
Degree of Doctor of Medicine and Surgery — 1986

University of Milan
Specialization in Gynecology and Obstetrics — 1985

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Latest publications

Eculizumab in a pregnant patient with laboratory onset of catastrophic antiphospholipid syndrome: A case report
Medicine (Baltimore). 2018 Oct;97(40):e12584.
Rovere-Querini P, Canti V, Erra R, Bianchi E, Slaviero G, D'Angelo A, Rosa S, Candiani M, Castiglioni MT.
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Antiphosphatidylserine/prothrombin Antibodies in Antiphospholipid Syndrome with Intrauterine Growth Restriction and Preeclampsia.
J Rheumatol. 2018 Aug;45(9):1263-1272. doi: 10.3899/jrheum.170751. Epub 2018 Jul 15
Canti V, Del Rosso S, Tonello M, Lucianò R, Hoxha A, Coletto LA, Vaglio Tessitore I, Rosa S, Manfredi AA, Castiglioni MT, Ruffatti A, Rovere-Querini P.
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Association of genetic variants in the 3'UTR of HLA-G with Recurrent Pregnancy Loss.
Hum Immunol. 2016 Oct;77(10):886-91.
Amodio G, Canti V, Maggio L, Rosa S, Castiglioni MT, Rovere-Querini P, Gregori S.
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Screenig for gestational diabetes in the Lombardy regio: A population based study.
Diabetes Metab 2015 Sep;41(4):319-25.
Nicotra F , Molinari C, Dozio N, Castiglioni MT , Ibrahim B , Zambob A , Corrao G , Scavini M
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The risk of preeclampsia beyond the first pregnancy among women with type 1 diabetes parity and preeclampsia in type 1 diabetes. Pregnancy Hypertension.
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health; 2014.
Castiglioni, M.T., Valsecchi, L, Cavoretto, P., Pirola, S.,Di Piazza, L., Maggio, L., Caretto, A., Garito, T.S., Rosa, S.,Scavini, M.
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