Daniele Lino Spagnolo


Dr. Daniele Lino Spagnolo directs the Functional Department of Prenatal Diagnostics and Ultrasound Diagnostics of the Department of Obstetrics and Gynecology, headed by Professor Massimo Candiani.

After graduating in 1981 from the Faculty of Medicine and Surgery of the University of Milan, the following year he received a master's degree in ultrasound in Obstetrics and Gynecology at the clinica Mangiagalli in Milan. In 1985, he again received a specialization in obstetrics and gynecology at the University of Milan. In 1988, he received a master's degree in prenatal diagnostics from Queen Charlotte Maternity Hospital in London.

Dr. Spagnolo is mainly engaged in obstetrics, both in the obstetric operating room and in the delivery room. In particular, he is an expert in prenatal, instrumental (level II ultrasound) and interventional diagnostics (willo-amniocentesis), gynecological ultrasound of the second level and in procedures under the control of ultrasound during gynecological ultrasound.

Dr. Daniele Lino Spagnolo is the author of more than 50 publications in scientific journals and book chapters on obstetrics and gynecology. His Hirsch index is 7. Permanent participant of national and international conferences.


University of Milan
Bachelor's Degree in Medicine and Surgery - 1981

University of Milan 1- Clinica Mangiagalli
Master's Degree in Obstetric and Gynecological ultrasound - 1982

University of Milan
Specialization in gynecology and obstetrics - 1988

Queen Charlotte Maternity Hospital in London
Master of Prenatal Diagnostics - 1997

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Latest publications

Transvaginal ultrasonography in persistent trophoblastic tumor
American Journal of Obstetrics and Gynecology. 169, 5, p. 1218-1223 6 p
Mangili, G., Spagnolo, D., Valsecchi, L. & Maggi, R.,
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Transvaginal sonography for fetal measurement in early pregnancy
British Journal of Obstetrics and Gynaecology. 99, 1, p. 38-42
Kustermann, A., Zorzoli, A., Spagnolo, D. & Nicolini, U., 1992
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Estimating the depth of myometrial involvement by endometrial carcinoma: efficacy of transvaginal sonography vs MR imaging
AJR Am J Roentgenol. 1993 Mar;160(3):533-8
DelMaschio A, Vanzulli A, Sironi S, Spagnolo D, Belloni C, Garancini P, Taccagni GL
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Transvaginal ultrasonography in persistent trophoblastic tumor
Am J Obstet Gynecol. 1993 Nov;169(5):1218-23
Mangili G, Spagnolo D, Valsecchi L, Maggi R.
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Sonographic endometrial thickness: A useful test to predict atrophy in patients with postmenopausal bleeding. An Italian multicenter study
Ultrasound in Obstetrics and Gynecology. 7, 5, p. 315-321 7 p
Ferrazzi, E., Torri, V., Trio, D., Zannoni, E., Filiberto, S., Dordoni, D., Amuso, G., Bocchi, C., Bonsignore, L., Brizzolara, M., Ceccarello, P. L., Colombo, D., Exacoustos, C., Galbiati, G., Gramellini, D., Lissoni, L., Luerti, M., Morici, A., Radaelli, U., Rusconi, C. Spagnolo D& 3 others, May 1996.
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Accuracy of the umbilical arteries Doppler flow velocity waveforms in detecting adverse perinatal outcomes in a high-risk populatio
Acta Obstet Gynecol Scand. 1996 Feb;75(2):113-9
Todros T, Ronco G, Fianchino O, Rosso S, Gabrielli S, Valsecchi L, Spagnolo D, Acanfora L, Biolcati M, Segnan N, Pilu G.
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Herniation of the amniotic sac into the bladder through a vesico-uterine fistula in the 32nd week of pregnancy
British Journal of Obstetrics and Gynaecology. 108, 12, p. 1300-1301 2 p.
Bertini, R., Roscigno, M., Colombo, R., Spagnolo, D., Ferrari, A. & Rigatti, P., 2001,
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Endometrial evaluation with transvaginal ultrasound during hormone therapy: a prospective multicenter study.
Fertil Steril. 2004 Jun;81(6):1632-7
Omodei U, Ferrazzi E, Ramazzotto F, Becorpi A, Grimaldi E, Scarselli G, Spagnolo D, Spagnolo L, Torri W.
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Percutaneous transvesical chorionic villus sampling: A safe alternative method for difficult procedures?
Ultrasound in Obstetrics and Gynecology. 44, 1, p. 115-116 2 p
Cavoretto, P., Dallagiovanna, C., Spagnolo, D. & Candiani, M., 2014
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Feto-neonatal ultrasonography to detect renal abnormalities: Evaluation of 1-year screening program
American Journal of Perinatology. 15, 3, p. 161-164 4 p.
Fasolato, V., Poloniato, A., Bianchi, C., Spagnolo, D., Valsecchi, L., Ferrari, A., Paesano, P. & Del Maschio, A., 1998
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Ultrasound imaging after evacuation as an adjunct to β-hCG monitoring in posthydatidiform molar gestational trophoblastic neoplasia
American Journal of Obstetrics and Gynecology. 2004
Garavaglia, E., Gentile, C., Cavoretto, P., Spagnolo, D., Valsecchi, L. & Mangili, G., Apr 2009
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Transvaginal ultrasound predicts delayed response to chemotherapy and drug resistance in Stage I low-risk trophoblastic neoplasia
Ultrasound in Obstetrics and Gynecology. 40, 1, p. 99-105 7 p
Cavoretto, P., Gentile, C., Mangili, G., Garavaglia, E., Valsecchi, L., Spagnolo, D., Montoli, S. & Candiani, M. Jul 2012
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Prenatal diagnosis by 3D ultrasound and MRI of an unusual malformation of cortical development with brain-in-brain appearance
Journal of Clinical Ultrasound. 37, 6, p. 354-359 6 p.
Valsecchi, L., Cavoretto, P., Di Piazza, L., Smid, M., Pontesilli, S., Scotti, R., Spagnolo, D. & Baldoli, C., Jul 2009
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Prenatal sonographic monitoring of idiopathic megacystis
Journal of Clinical Ultrasound. 41, 2, p. 116-118 3 p
Cavoretto, P., Lesma, A., Spagnolo, D., Valsecchi, L., Negretto, A. & Candiani, M., Feb 2013,
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