Carlo Pappone - To make an appointment - GSD - a group of clinics in Italy

Biography

Prof. Carlo Pappone is the Head of the Operative Unit of Clinical Arithmology and the Electrophysiology Laboratory at IRCCS Policlinico San Donato in Milan, as well as Cardiologist, Arithmologist and Electrophysiologist at Casa di Cura La Madonnina.

In 1986, he graduates in Medicine and Surgery from the University Federico II of Naples, where he obtains specialization in Cardiology four years later, and in 1995, he obtains PhD in Cardiovascular Diseases at the University of Tor Vergata in Rome.

Prof. Pappone is involved in all electrophysiology procedures, with particular interest in transcatheter ablation of atrial fibrillation, supraventricular tachycardias and Wolff Parkinson White (WPW) syndrome, in adult and pediatric population.

In scientific research, he focuses on the development of new therapeutic strategies in patients with atrial fibrillation and WPW, and the prevention of sudden arrhythmic death of arrhythmogenic congenital heart diseases.

In recent time, his focus of interest has turned to the prevention of sudden death and the treatment of ventricular arrhythmias in patients with Brugada syndrome. He developed a new epicardial ablation procedure to identify and eliminate the mechanisms that trigger sudden death in these patients: to date, approximately 500 patients have been successfully treated.

Dr Pappone is invited speaker and moderator at major national and international congresses in the field of cardiology and arrhythmology; author of 184 scientific articles, more than 30 book chapters and 184 papers (16,814 citations, H-Index 50).

He is a reviewer of numerous journals, such as New England Journal of Medicine, Lancet, Annals of Internal Medicine, Journal of the American College of Cardiology, JAMA, Circulation, European Heart Journal, American Heart Journal, American Journal of Cardiology, Circulation Arrhytmia Electrophisiology, Europace, Heart Rhythm, Journal of the American Medical Association, Journal of Cardiovascular Electrophysiology, Journal of Cardiovascular Medicine, Giornale Italiano di Cardiologia and Giornale Italiano di Aritmologia e Cardiostimolazione.

In 2006, he is given the Elite Reviewer Award from the Editorial Board of the Journal of the American College of Cardiology (JACC). He is a Fellow in numerous international cardiology societies, such as American Heart Association (AHA), European Society of Cardiology (ESC) and American College of Cardiology (ACC).

For more information, please visit the Prof. Pappone’s website: www.af-ablation.org

Education

University Federico II of Naples

Degree in Medicine – 1986

Multimedia gallery

The Effectiveness of Arrhythmic Substrate Ablation in The Treatment of Brugada Syndrome Has Been Confirmed

Publications

He is an author of 184 scientific articles, more than 30 book chapters and 184 papers (16,814 citations, H-Index 50).

He is a reviewer of numerous journals, such as New England Journal of Medicine, Lancet, Annals of Internal Medicine, Journal of the American College of Cardiology, JAMA, Circulation, European Heart Journal, American Heart Journal, American Journal of Cardiology, Circulation Arrhytmia Electrophisiology, Europace, Heart Rhythm, Journal of the American Medical Association, Journal of Cardiovascular Electrophysiology, Journal of Cardiovascular Medicine, Giornale Italiano di Cardiologia and Giornale Italiano di Aritmologia e Cardiostimolazione.

Latest publications

Assessing the Malignant Ventricular Arrhythmic Substrate in Patients With Brugada Syndrome

J Am Coll Cardiol. 2018 Apr 17;71(15):1631-1646. doi: 10.1016/j.jacc.2018.02.022. PMID: 29650119

Pappone C, Ciconte G, Manguso F, Vicedomini G, Mecarocci V, Conti M, Giannelli L, Pozzi P, Borrelli V, Menicanti L, Calovic Z, Della Ratta G, Brugada J, Santinelli V.

Electrical Substrate Elimination in 135 Consecutive Patients With Brugada Syndrome.

Circulation Arrhythmia Electrophysiology. 2017(5):e005053. doi: 10.1161/CIRCEP.117.005053

Pappone C, Brugada J, Vicedomini G, Ciconte G, Manguso F, Saviano M, Vitale R, Cuko A, Giannelli L, Calovic Z, Conti M, Pozzi P, Natalizia A, Crisà S, Borrelli V, Brugada R, Sarquella- Bruga

Brugada Syndrome Phenotype Elimination by Epicardial Substrate Ablation

Circulation Arrhythmia Electrophysiology. 2015 Dec;8(6):1373-81

Brugada J, Pappone C (both first Authors), Berruezo A, Vicedomini G, Manguso F, Ciconte G, Giannelli L, Santinelli V.

Wolff-Parkinson-White syndrome in the era of catheter ablation: insights from a registry study of 2169 patients

Circulation. 2014 Sep 2;130(10):811-9

Pappone C, Vicedomini G, Manguso F, Saviano M, Baldi M, Pappone A, Ciaccio C, Giannelli L, Ionescu B, Petretta A, Vitale R, Cuko A, Calovic Z, Fundaliotis A, Moscatiello M, Tavazzi L, Santinelli V.

Risk of Malignant Arrhythmias in Initially Symptomatic Patients with WPW Syndrome: Results of a Prospective Long-Term Electrophysiological Follow-Up Study

Circulation. 2012 ;125:661-8

Pappone C, Vicedomini G, Manguso F, Baldi M, Pappone A, Petretta A, Vitale R, Saviano M, Ciaccio C, Giannelli L, Calovic Z, Tavazzi L, Santinelli V.

ThermoCool AF Trial Investigators. Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial

JAMA 2010; 303:333-40

Wilber DJ, Pappone C, Neuzil P, De Paola A, Marchlinski F, Natale A, Macle L, Daoud EG, Calkins H, Hall B, Reddy V, Augello G, Reynolds MR, Vinekar C, Liu CY, Berry SM, Berry DA;

The natural history of asymptomatic ventricular preexcitation. A long-term prospective follow-up study of 184 asymptomatic children

J Am Coll Cardiol. 2009; 53: 275-280

Santinelli V, Radinovic A, Manguso F, Vicedomini G, Gulletta S, G Paglino, Mazzone P, Ciconte G, Sacchi S, Sala S, Pappone C.

New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome. Prevalence and clinical significance.

Eur. Heart J. 2009; 30: 2985-92.

Pappone C, Radinovic A, Manguso F, Vicedomini G, Sala S, Sacco FM, Ciconte G, Saviano M, Ferrari M, Sommariva E, Sacchi S, Ciaccio C, Santinelli V.

Robotic Magnetic Navigation for Atrial Fibrillation Ablation.

J Am Coll Cardiol. 2006 Apr 7;47 (7): 1390-400

Pappone C, Vicedomini G, Manguso F, Mazzone P, Gugliotta F, Sala S, Sora N, Paglino G, Gulletta S, Ciaccio C, Tortoriello V, Del Torchio S, Santinelli V.

Circumferential pulmonary vein ablation for chronic atrial fibrillation: a randomized, controlled study.

The New Engl J Med 2006 2;354:934-94.

Oral H, Pappone C (both, first Authors), Chugh A, Good E, Bogun F, Pelosi F, Bates E , Lehmann M, Vicedomini G, Augello G, Agricola E, Sala S, Santinelli V, Morady F.