The Transfusion Center at Princess Christian Maternity Hopital (PCMH) was built and inaugurated in Freetown in December 2019. Planned equipment was delivered and installed (refrigerators, professional laboratory counters, centrifuges, platelet stirrer, thermostatic bath, donation chairs complete with accessories, office furniture). AISPO supplied with consumables and reagents (Anti-A/B/AB/D/Phenotypes (C, c, E, e), Anti-Kell, rapid tests for HIV, Hepatitis and syphilis, cannulae, pipettes Pasteur, vacutainer, microscope slides, hemocue cuvettes, single and quadruple blood bags, sanitizing gels, rapid test for malaria, stock cards and other stationery necessary for the laboratory). Production of blood components (plasma, platelets, red blood cells) started in March 2020. A database for blood donor data collection was created and a new software for patients registration is being developed. An outreach campaign was implemented and 176 donors participated and donated bloods. Four scholarships were sponsored during the project and the sierraleonians scholars were welcomed for one month at the San Raffaele Transfusion center in Milan for the theroetical and on-the-job training. Missions of experts (hospital management, San Raffaele Transfusion Center experts, doctor as Project Manager and laboratorist) were done during the three years. 9 Standard Operating Procedures (SOPs) were developed by transfusion center expert during the first year of the project. Training of 32 laboratory technicians involved in methods of production and review of blood derivatives.