Francesca Lorentino

Biography

Dr. Francesca Lorentino is a hematologist and transplant specialist in the Department of Hematology and Bone Marrow Transplantation at the IRCCS Ospedale San Raffaele, headed by Professor Fabio Ciceri.

After graduating in 2011 from the Faculty of Medicine and Surgery of the Vita Salute San Raffaele University, she specialized in hematology in 2017 at the same university. Since November 2020, he has been receiving a doctorate in public health, biostatistics and epidemiology from the University of Milan Bicocca. During her studies, she completed an internship abroad, where she had the opportunity to collaborate, for example, with the EBMT Working Party on Acute Leukemia, based in Paris: here she served as the main researcher of multicenter registration studies of patients who underwent allogeneic bone marrow transplantation.

From a clinical point of view, Dr. Lorentino mainly works with patients with hematological malignancies who have undergone allogeneic bone marrow transplantation, gene therapy and cell therapy, such as chimeric antigenic T-cell receptors (CAR-T cells).

As a researcher, the doctor is currently involved in conducting clinical trials within: GITMO, Acute Leukemia Working Party and Cellular Therapy and Immunobiology Working Party DELL'EBMT.

He is the author and co-author of 25 publications in national and international scientific journals and book chapters. Constantly participates in national and international industry conferences.

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Publications

Latest publications

Microbiome Markers are Early Predictors of Acute GvHD in Allogeneic Hematopoietic Stem Cell Transplant recipients
Blood. 2020 Nov 10:blood.2020007158. doi: 10.1182/blood.2020007158.
Greco R, Nitti R, Mancini N, Pasciuta R, Lorentino F, Lupo-Stanghellini MT, Barbanti MC, Clementi N, Giglio F, Clerici D, Marktel S, Assanelli AA, Carrabba MG, Bernardi M, Corti C, Peccatori J, Clementi M, Ciceri F.
Donor Lymphocyte Infusions After Allogeneic Stem Cell Transplantation in Acute Leukemia: A Survey From the Gruppo Italiano Trapianto Midollo Osseo (GITMO)
Front Oncol. 2020 Oct 15;10:572918. doi: 10.3389/fonc.2020.572918. eCollection 2020.
Patriarca F, Sperotto A, Lorentino F, Oldani E, Mammoliti S, Isola M, Picardi A, Arcese W, Saporiti G, Sorasio R, Mordini N, Cavattoni I, Musso M, Borghero C, Mic  C, Fanin R, Bruno B, Ciceri F, Bonifazi F.
Post-transplantation cyclophosphamide GvHD prophylaxis after hematopoietic stem cell transplantation from 9/10 or 10/10 HLA-matched unrelated donors for acute leukemia
Leukemia. 2020 May 14. doi:10.1038/s41375-020-0863-4. Online ahead of print.
Lorentino F, Labopin M, Ciceri F, Vago L, Fleischhauer K, Afanasyev B, Kr ger N, Cornelissen JJ, Lovira M, Meijer E, Vitek A, Elmaagacli A, Blaise D, Ruggeri A, Chabannon C, Nagler A, Mohty M; Acute Leukemia Working Party (ALWP) and Cellular Therapy and Immunobiology Working Party (CTIWP) of the European Society for Blood and Marrow Transplantation (EBMT).
Mechanisms of Leukemia Immune Evasion and Their Role in Relapse After Haploidentical Hematopoietic Cell Transplantation
Front Immunol. 2020 Feb 25;11:147. doi: 10.3389/fimmu.2020.00147. eCollection 2020.
Rovatti PE†, Gambacorta V†, Lorentino F†, Ciceri F, Vago L. †= equal contribution.
Infections after Allogenic Transplant with Post-Transplant Cyclophosphamide: Impact of Donor HLA Matching
Biol Blood Marrow Transplant. 2020 Jun;26(6):1179-1188. doi: 10.1016/j.bbmt.2020.01.013. Epub 2020 Jan 28.
Oltolini C, Greco R, Galli L, Clerici D, Lorentino F, Xue E, Lupo Stanghellini MT, Giglio F, Uhr L, Ripa M, Scarpellini P, Bernardi M, Corti C, Peccatori J, Castagna A, Ciceri F.
Interleukin-6 as Biomarker for Acute GvHD and Survival After Allogeneic Transplant With Posttransplant Cyclophosphamide
Front. Immunol., 01 October 2019 |
Raffaella Greco†, Francesca Lorentino†, Rosamaria Nitti, Maria Teresa Lupo Stanghellini, Fabio Giglio, Daniela Clerici, Elisabetta Xue, Lorenzo Lazzari, Simona Piemontese, Sara Mastaglio, Andrea Assanelli, Sarah Marktel, Consuelo Corti, Massimo Bernardi, Fabio Ciceri††and Jacopo Peccatori†. †= equal contribution.
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Comparative evaluation of biological human leukocyte antigen DPB1 mismatch models for survival and graft-versus-host disease prediction after unrelated donor hematopoietic cell transplantation
Haematologica. 2020 Apr;105(4):e186-e189. doi: 10.3324/haematol.2019.225177. Epub 2019 Aug 30.
Lorentino F, Sacchi N, Oldani E, Miotti V, Picardi A, Gallina AM, Crivello P, Bernasconi P, Saccardi R, Farina L, Benedetti F, Cerno M, Grassi A, Bruno B, Patriarca F, Ciceri F, Fleischhauer K, Vago L, Bonifazi F.
Comparable outcomes of haploidentical, 10/10 and 9/10 unrelated donor transplantation in adverse karyotype AML in first complete remission
Am J Hematol. 2018 Oct;93(10):1236-1244. doi: 10.1002/ajh.25231. Epub 2018 Sep 3.
Lorentino F, Labopin M, Bernardi M, Ciceri F, Soci  G, Cornelissen JJ, Esteve J, Ruggeri A, Volin L, Yacoub-Agha I, Craddock C, Passweg J, Blaise D, Gedde-Dahl T, Poiani M, Fegueux N, Mohty M, Nagler A; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.
Killer cell immunoglobulin-like receptor ligand mismatching and outcome after haploidentical transplantation with post-transplant cyclophosphamide
Leukemia. 2019 Jan;33(1):230-239. doi: 10.1038/s41375-018-0170-5. Epub 2018 Jun 15.
Shimoni A, Labopin M, Lorentino F, Van Lint MT, Koc Y, Gülbas Z, Tischer J, Bruno B, Blaise D, Pioltelli P, Afanasyev B, Ciceri F, Mohty M, Nagler A.
The impact of HLA matching on outcomes of unmanipulated haploidentical HSCT is modulated by GVHD prophylaxis
Blood Advances 2017 1:669-680; doi:
Francesca Lorentino, Myriam Labopin, Katharina Fleischhauer, Fabio Ciceri, Carlheinz R. Mueller, Annalisa Ruggeri, Avichai Shimoni, Martin Bornh user, Andrea Bacigalupo, Zafer Gülbas, Yener Koc, William Arcese, Benedetto Bruno, Johanna Tischer, Didier Blaise, Giuseppe Messina, Dietrich W. Beelen, Arnon Nagler and Mohamad Mohty.
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NK cell recovery after haploidentical HSCT with post-transplant cyclophosphamide: dynamics and clinical implications
Blood 2017 :blood-2017-05-780668; doi:
Antonio Russo, Giacomo Oliveira, Sofia Berglund, Raffaella Greco, Valentina Gambacorta, Nicoletta Cieri, Cristina Toffalori, Laura Zito, Francesca Lorentino, Simona Piemontese, Mara Morelli, Fabio Giglio, Andrea Assanelli, Maria Teresa Lupo Stanghellini, Chiara Bonini, Jacopo Peccatori, Fabio Ciceri,Leo Luznik and Luca Vago.
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Post-transplant cyclophosphamide and Sirolimus after Haploidentical HSCT Using a Treosulfan-based myeloablative conditioning and PBSC
Blood. 2016 Sep 15;128(11):1528-31.
Nicoletta Cieri MD, Raffaella Greco, Lara Crucitti, Mara Morelli, Fabio Giglio, Giorgia Levati, Andrea Assanelli, Matteo Carrabba, Laura Bellio, Raffaella Milani, Francesca Lorentino, Maria Teresa Lupo Stanghellini, Tiago De Freitas, Sarah Marktel, Massimo Bernardi, Consuelo Corti, Luca Vago, Chiara Bonini, Fabio Ciceri and Jacopo Peccatori. BBMT, 015 Aug;21(8):1506-14. Posttransplantation cycloph
Control of infectious mortality due to carbapenemase-producing Klebsiella pneumoniae in hematopoietic stem cell transplantation
Bone Marrow Transplant. 2016 Sep 26.
Forcina A, Baldan R, Marasco V, Cichero P, Bondanza A, Noviello M, Piemontese S, Soliman C, Greco R, Lorentino F, Giglio F, Messina C, Carrabba M, Bernardi M, Peccatori J, Moro M, Biancardi A, Nizzero P, Scarpellini P, Cirillo DM, Mancini N, Corti C, Clementi M, Ciceri F.
Post-transplant cyclophosphamide versus antithymocyte-globulin as graft versus host disease prophylaxis in haploidentical transplant
Haematologica. 2016 Oct 6.
Ruggeri A, Sun Y, Labopin M, Bacigalupo A, Lorentino F, Arcese W, Santarone S, Gülbas Z, Blaise D, Messina G, Ghavamzadeh A, Malard F, Bruno B, Diez-Martin JL, Koc Y, Ciceri F, Mohty M, Nagler A.

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