Claudio Grignani

Dr. Claudio Grignani is an internist at the Internal Medicine Unit of the Istituto Clinico Beato Matteo.

He graduated with honors in Medicine and Surgery from the University of Pavia in 2006.In 2012, he earned a diploma in ultrasound from the SIUMB School of Infectious Diseases at the San Matteo Polyclinic in Pavia. That same year, he also completed a specialization in Internal Medicine with honors at the Clinical Medicine Unit of the San Matteo Polyclinic in Pavia.

Since 2007, Dr. Grignani has been involved in patient care in Internal Medicine wards. From 2007 to 2012, he worked at the III Medical Clinic of San Matteo in Pavia. Since 2012, he has been serving in the ward at the Istituto Clinico Beato Matteo in Vigevano. Dr. Grignani was the lead internist managing a COVID ward during both waves of the pandemic. Currently, he oversees biologic drug therapy for the treatment of autoimmune diseases in the hospital’s day hospital (DH).

He is also involved in the diagnosis and treatment of acute conditions, particularly in elderly patients with multiple pathologies. He performs invasive procedures such as:

• Thoracentesis
• Paracentesis
• Bone biopsy
• Liver biopsy

Dr. Grignani manages the internal medicine outpatient clinic for chronic patients and the abdominal ultrasound clinic. In the internal medicine outpatient clinic, he prescribes and renews therapeutic plans for new oral anticoagulants (NOACs) and monoclonal antibodies used in osteoporosis treatment.

He has numerous publications, including:

• “In vitro platelet aggregation defects in patients with myeloproliferative disorders and high platelet counts: are they laboratory artefacts?” published in Platelets (March 2009)
• “Clinical and laboratory features of 103 patients from 42 Italian families with inherited thrombocytopenia derived from the monoallelic Ala156Val mutation of GPIb{alpha} (Bolzano mutation)” published in Haematologica(September 2011)
• “TPO and IL-6 in patients with acute phase reaction with or without thrombocytosis” in the abstract volume of the XIX Congress of the Italian Society for the Study of Haemostasis and Thrombosis (Milan, September 14-17, 2006)
• “Are the platelet function defects in patients with clonal thrombocytosis artefactual?” published in the Bollettino della Società Medico Chirurgica di Pavia (April 2007)
• “Phenotypic and genotypic characterization of 93 cases of inherited thrombocytopenia” in the Bollettino della Società Medico Chirurgica di Pavia (April 2007)
• “Cyclic EDTA-induced pseudothrombocytopenia (PTCP): a new condition?” in the abstract volume of the XX Congress of the Italian Society for the Study of Haemostasis and Thrombosis (Florence, September 25-28, 2008)
• “On a case of hemophagocytic syndrome associated with visceral leishmaniasis” in the abstract volume of the 109th National Congress of the Italian Society of Internal Medicine (Genoa, October 25-28, 2008)
• “Hyperinfection syndrome due to Strongyloides stercoralis in a patient with plasmacytoma” in the abstract volume of the 109th National Congress of the Italian Society of Internal Medicine (Genoa, October 25-28, 2008)
• “Panniculitis of the lower limbs in a patient with myelofibrosis with myeloid metaplasia” in the abstract volume of the 109th National Congress of the Italian Society of Internal Medicine (Genoa, October 25-28, 2008).