Alberto Davalli

Biography

Dr. Alberto Davalli is Senior Physician in the Department of Endocrine and Diabetological General Medicine at the Ospedale San Raffaele Clinical Research Institute, headed by Professor Emanuele Bosi.

After graduating in 1985 from the Faculty of Medicine and Surgery of the University of Milan, he specialized in Diabetology and Metabolic Disorders in 1989 and in Endocrinology and Metabolic Disorders in 2004 at the same university.

Dr. Davalli is involved in clinical activities in the department and in the outpatient clinic as an internal medicine physician, diabetologist and endocrinologist.

In terms of research, Dr. Davalli has held a number of prominent positions, both nationally and internationally, in the field of diabetology and endocrinology research. He is the author and co-author of 90 publications in industry scientific journals and chapters in books. His Hirsch index is 34. He regularly participates in national and international industry congresses.

Do you need an appointment?

Contact us and we will take care of you.

Publications

Latest publications

Abnormal sensitivity to glucose of human islets cultured in a high glucose medium: partial reversebility after an additional culture in a normal glucose medium.
J Clin Endocrinol Metab 72 (1): 202-208, 1991
Davalli AM, Ricordi C, Socci C, Braghi S, Bertuzzi F, Fattor B, Di Carlo V, Pontiroli AE, Pozza G.
Human islets chronically exposed in-vitro to different stimuli become unresponsive to the same stimuli given acutely: evidence supporting specific desensitization rather than b-cell exhaustion.
J Clin Endocrinol Metab, 74:790-794, 1992
Davalli AM, Pontiroli AE, Socci C, Bertuzzi F, Fattor B, Braghi S, Di Carlo V, Pozza G.
Paradoxical release of insulin by adult pig islet in-vitro: recovery after culture in a defined tissue culture medium.
Transplantation, 56: 148-154, 1993
Davalli AM, Bertuzzi F, Socci C, Scaglia L, Gavazzi F, M. Freschi, Di Carlo V, Pontiroli AE, Pozza G.
Loss of glucose-induced insulin secretion and Glut 2 expression in transplanted beta cells.
Diabetes, 44:75-79, 1995
Ogawa Y, Noma Y, Davalli AM, WU Y-J, Thorens B, Bonner-Weir S, Weir GC.
Function, mass, and replication of porcine and rat islets transplanted into diabetic nude mice.
Diabetes, 44:104-111, 1995
Davalli AM, Ogawa Y, Scaglia L, Wu Y-J, Hollister Jennifer, Bonner-Weir S, Weir GC.
Selective decrease in the beta cell mass of human islets transplanted into diabetic nude mice.
Transplantation, 59:817-820, 1995
Davalli AM, Ogawa Y, Ricordi C, Scharp DW, Bonner-Weir S, Weir GC
Long-term normalization of GLUT-4 protein content in skeletal muscle of diabetic rats following islet transplantation.
Journal of Endocrinology, 150:255-263, 1996
Davalli AM, Napoli R, Weitgasser R, Hirshman MF, Capotorto JV, Finegood DT, Bonner-Weir S, Horton ES, Weir GC.
Islet transplantation under the kidney capsule fully corrects the impaired skeletal muscle glucose transport system of streptozotocin diabetic rats.
J Clin Invest, 97: 1389-1397, 1996
Napoli R, Davalli AM, Hirshman MF, Weitgasser R, Weir GC, Horton ES.
Vulnerability of islets in the immediate post-transplantation period: dynamic changes in structure and function
Diabetes, 45:1161 - 1167, 1996
Davalli AM, Scaglia L, Zangen DH, Hollister J, Bonner-Weir S, Weir GC.
Insulin-secreting nonislet cells are resistant to autoimmune destruction
Proc. Natl. Acad. Sci. (USA), 93:8595-8600, 1996
Lipes MA, Cooper E, Skelly R, Rhodes CJ, Boschetti EV, Weir GC, Davalli AM.
Pituitary cotransplantation significantly improves the performance, insulin content, and vascularization of renal subcapsular islet grafts
Diabetes, 48:59-65,1999
Davalli AM, Scaglia L, Brevi M, Sanvito F, Freschi M, Cavallaro U, Parlow A, Pontiroli AE.
Insights from a successful case of intrahepatic islet transplantation into a type 1 diabetic patient
J Clin Endocrinol Metab, 85:3847-3852, 2000
Davalli AM, Maffi P, Socci C, Sanvito F, Freschi M, Bertuzzi F, Falqui L, Di Carlo V, Pozza G, Secchi A.
The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPKdependent mechanism
J Transl Med. 2016 Jul 30;14(1):229
Andreozzi F, Raciti GA, Nigro C, Mannino GC, Procopio T, Davalli AM, Beguinot F, Sesti G, Miele C, Folli F.
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death
J Biol Chem. 2011 Apr 22;286(16):14007-18
Di Cairano ES, Davalli AM, Perego L, Sala S, Sacchi VF, La Rosa S, Finzi G, Placidi C, Capella C, Conti P, Centonze VE, Casiraghi F, Bertuzzi F, Folli F, Perego C.
Halff GA, DeFronzo RA, Folli F.Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas.
JCI Insight. 2019 Oct 17;4(20).
Fiorentino TV, Casiraghi F, Davalli AM, Finzi G, La Rosa S, Higgins PB, Abrahamian GA, Marando A, Sessa F, Perego C, Guardado-Mendoza R, Kamath S, Ricotti A, Fiorina P, Daniele G, Paez AM, Andreozzi F, Bastarrachea RA, Comuzzie AG, Gastaldelli A, Chavez AO, Di Cairano ES, Frost P, Luzi L, Dick EJ,

Do you need an appointment?

Contact us and we will take care of you.