Paolo Prospero Ghia - 预约 - GSD - 意大利医院集团

个人简介

Paolo Ghia教授是CLL战略项目的主任，也是圣拉斐尔科学研究医院B细胞肿瘤研究科室的负责人。此外，他还是圣拉斐尔生命健康大学肿瘤内科的正教授。

在临床和研究领域，Ghia教授三十年来一直致力于开展肿瘤血液学的转化研究，尤其是惰性白血病/淋巴瘤（包括慢性淋巴细胞白血病[CLL]）的转化研究。

Paolo Ghia教授是多个国际科学协会的成员，包括：

GIMEMA（意大利成人恶性血液病组）淋巴细胞增生性疾病工作组共同主席、
CLL国际研讨会（iwCLL）成员、
GIMEMA（意大利成人恶性血液病组）淋巴细胞增生性疾病工作组成员、
欧洲CLL研究倡议（ERIC）主席、
WHO淋巴细胞和组织细胞恶性肿瘤临床咨询委员会成员、
Henry Kunkel学会（美国纽约）成员。

教育背景

都灵大学
1990年，医学博士学位

都灵大学
1996年，人类肿瘤领域博士研究生

都灵大学（Polo di Orbassano）
2003年，内科学专业学位

出版物

最新出版物

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.

Haematologica. 2017 Jun;102(6):1085-1090. doi: 10.3324/haematol.2016.157552. PMID: 28255015

Wu SJ, Lin CT, Agathangelidis A, Lin LI, Kuo YY, Tien HF, Ghia P.

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Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.

Nat Commun. 2017 Jun 9;8:15746. doi: 10.1038/ncomms15746.

Minici C, Gounari M, Übelhart R, Scarfò L, Dühren-von Minden M, Schneider D, Tasdogan A, Alkhatib A, Agathangelidis A, Ntoufa S, Chiorazzi N, Jumaa H, Stamatopoulos K, Ghia P*, Degano M. *Corresponding author and co-senior author.

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Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations.

Haematologica. 2018 Feb 15. pii: haematol.2017.177212. doi: 10.3324/haematol.2017.177212.

Agathangelidis A, Ljungström V, Scarfò L, Fazi C, Gounari M, Pandzic T, Sutton LA, Stamatopoulos K, Tonon G, Rosenquist R, Ghia P.

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Efficacy of bendamustine and rituximab as first salvage treatment in chronic lymphocytic leukemia and indirect comparison with ibrutinib: a GIMEMA, ERIC and UK CLL FORUM study.

Haematologica. 2018 Apr 19. pii: haematol.2018.189837. doi: 10.3324/haematol.2018.189837. [Epub ahead of print]PMID: 29674504

Cuneo A, Follows G, Rigolin GM, Piciocchi A, Tedeschi A, Trentin L, Medina Perez A, Coscia M, Laurenti L, Musuraca G, Farina L, Rivas Delgado A, Orlandi EM, Galieni P, Mauro FR, Visco C, Amendola A, Billio A, Marasca R, Chiarenza A, Meneghini V, Ilariucci F, Marchetti M, Molica S, Re F, Gaidano G, Gonzalez M, Forconi F, Ciolli S, Cortelezzi A, Montillo M, Smolej L, Schuh A, Eyre TA, Kennedy B, Bow

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Minimal residual disease analysis in chronic lymphocytic leukemia: a way for achieving more personalized treatments.

Leukemia. 2018 Jun;32(6):1307-1316. doi: 10.1038/s41375-018-0109-x. Epub 2018 Mar 26. PMID: 29700386.

Ghia P, Rawstron A.

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Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: extended phase 3 results from RESONATE-2.

Haematologica. 2018 Jun 7. pii: haematol.2018.192328. doi: 10.3324/haematol.2018.192328. PMID: 29880603.

Barr PM, Robak T, Owen C, Tedeschi A, Bairey O, Bartlett NL, Burger JA, Hillmen P, Coutre S, Devereux S, Grosicki S, McCarthy H, Li J, Simpson D, Offner F, Moreno C, Zhou C, Styles L, James D, Kipps TJ, Ghia P.

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A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.

Oncotarget. 2018 May 25;9(40):26019-26031. doi: 10.18632/oncotarget.25419. eCollection 2018 May 25. PMID: 29899839.

Primo D, Scarfò L, Xochelli A, Mattsson M, Ranghetti P, Espinosa AB, Robles A, Gorrochategui J, Martínez-López J, de la Serna J, González M, Gil AC, Anguita E, Iraheta S, Munugalavadla V, Quéva C, Tannheimer S, Rosenquist R, Stamatopoulos K, Ballesteros J, Ghia P.

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High-risk chronic lymphocytic leukemia in the era of pathway inhibitors: Integrating molecular and cellular therapies.

Blood. 2018 Jul 11. pii: blood-2018-01-826008. doi: 10.1182/blood-2018-01-826008. PMID: 29997221.

Dreger P, Ghia P, Schetelig J, van Gelder M, Kimby E, Michallet M, Moreno C, Robak T, Stilgenbauer S, Montserrat E.

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Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies.

Am J Hematol. 2018 Aug 20. doi: 10.1002/ajh.25259. PMID: 30129285.

Robak T, Burger JA, Tedeschi A, Barr PM, Owen C, Bairey O, Hillmen P, Simpson D, Grosicki S, Devereux S, McCarthy H, Coutre SE, Quach H, Gaidano G, Maslyak Z, Stevens DA, Moreno C, Gill DS, Flinn IW, Gribben JG, Mokatrin A, Cheng M, Styles L, James DF, Kipps TJ, Ghia P.

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Dichotomous Toll-like receptor responses in chronic lymphocytic leukemia patients under ibrutinib treatment.

Leukemia. 2019 Jan 3. doi: 10.1038/s41375-018-0335-2. PMID: 30607020

Gounari M, Ntoufa S, Gerousi M, Vilia MG, Moysiadis T, Kotta K, Papakonstantinou N, Scarfò L, Agathangelidis A, Fonte E, Ranghetti P, Nenou A, Xochelli A, Coscia M, Tedeschi A, Stavroyianni N, Muzio M, Stamatopoulos K, Ghia P.

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