Vanesa Gregorc

Biography

Doctor Vanesa Gregorc is a Senior Consultant at the Department of Oncology and at the Research Division of Molecular Oncology at the San Raffaele Research Hospital in Milan, Italy. Holds a position of Professor of International Program course in Oncology at the Faculty of Medicine and Surgery at the Vita- Salute San Raffaele University.

Professor Gregorc is a General Secretary of Lung Working Group of the Alliance Against Cancer: the excellence network of Italian Cancer Institutes; a member of the following working groups: melanoma, immunology and genomics.

Doctor Gregorc manages 25 clinical trials and 3 research projects simultaneously. She was involved in more than 50 clinical trials and conducted the Investigators Initialed Trials. One of these, the Prose, had been presented in the main Lung Cancer session at ASCO 2013 and had been included in the NCCI Guidelines. Doctor Gregorc has a permanent collaboration with the Italian Ministry of Health and Pharma companies.

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Publications

Latest publications

Aspetti psicologici del tumore del polmone. Capitolo del libro “Psiconcologia"
P. Catanzaro, V. Gregorc.
Mesotelioma, Eziopatogenesi, presentazione clinica e percorso diagnostico-terapeutico
Medicina e Diritto 3/2009, Sessione Focus. pg 14-23, Maggioli Editore
Ghio D, Gregorc V.
Relevance Of P53, Bcl-2 And Rb Expression On Resistance To Cisplatin-Based Chemotherapy In Advanced Non Small Cell Lung Cancer (NSCLC)
Lung Cancer (2003) 41-48
V. Gregorc, V. Ludovini, L. Pistola, S. Darwish, I. Floriani, G. Bellezza, A. Sidoni, A. Cavaliere, M. Scheibel, V. De Angelis, E. Bucciarelli, M. Tonato.
Prognostic value of circulating chromogranin A and soluble tumor necrosis factor receptors in advanced nonsmall cell lung cancer
Cancer. 2007 Aug 15;110(4):845-53.
Gregorc V, Spreafico A, Floriani I, Colombo B, Ludovini V, Pistola L, Bellezza G, Vigano MG, Villa E, Corti A.
Germline polymorphisms in EGFR and survival in patients with lung cancer receiving gefitinib
Clin Pharmacol Ther. 2008 Mar;83(3):477-84.
Gregorc V, Hidalgo M, Spreafico A, Cusatis G, Ludovini V, Ingersoll RG, Marsh S, Steinberg SM, Viganò MG, Ghio D, Villa E, Sparreboom A, Baker SD.
Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
Br J Cancer. 2009 Jul 21;101(2):21924.
Gregorc V, Santoro A, Bennicelli E, Punt CJ, Citterio G, Timmer-Bonte JN, Caligaris Cappio F, Lambiase A, Bordignon C, van Herpen CM.
Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.
Lancet Oncol. 2014 Jun;15(7):713-21.
Gregorc V, Novello S, Lazzari C, Barni S, Aieta M, Mencoboni M, Grossi F, Pas TD, de Marinis F, Bearz A, Floriani I, Torri V, Bulotta A, Cattaneo A, Grigorieva J, Tsypin M, Roder J, Doglioni C, Levra MG, Petrelli F, Foti S, Viganò M, Bachi A, Roder H.
Randomized Phase III Trial of Erlotinib versus Docetaxel in Patients with Advanced Squamous Cell Non-Small Cell Lung Cancer Failing First-Line PlatinumBased Doublet Chemotherapy Stratified by VeriStrat Good versus VeriStrat Poor
The European Thoracic Oncology Platform (ETOP) EMPHASIS-lung Trial J Thorac Oncol. J Thorac Oncol. 2017 Apr;12(4):752-762
Peters S, Stahel RA, Dafni U, Ponce Aix S, Massutí B, Gautschi O, Coate L, López Martín A, van Heemst R, Berghmans T, Meldgaard P, Cobo Dols M, Garde Noguera J, Curioni-Fontecedro A, Rauch D, Mark MT, Cuffe S, Biesma B, van Henten AM, Juan Vidal Ó, Palmero Sanchez R, Villa Guzmán JC, Collado Martin R, Peralta S, Insa A, Summers Y, Láng I, Horgan A, Ciardiello F, de Hosson S, Pieterman R, Groen HJ,
Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer
J Thorac Dis. 2018 Nov;10(Suppl 33):S4023-S4027. doi: 10.21037/jtd.2018.10.17.
Petrelli F, Lazzari C, Ardito R, Borgonovo K, Bulotta A, Conti B, Cabiddu M, Capitanio JF, Brighenti M, Ghilardi M, Gianni L, Barni S, Gregorc V. Efficacy of ALK inhibitors on NSCLC brain metastases: A systematic review and pooled analysis of 21 studies. PLoS One. 2018 Jul 27;13(7):e0201425. doi: 10.1371/journal.pone.0201425. eCollection 2018. Lazzari C, Gregorc V, Cangi MG, Giovannetti E, Bulotta
PD-1 Inhibitors-Related Neurological Toxicities in Patients with Non-Small-Cell Lung Cancer: A Literature Review. Cancers (Basel)
2019 Mar 1;11(3). pii: E296. doi: 10.3390/cancers11030296.
Mirabile A, Brioschi E, Ducceschi M, Piva S, Lazzari C, Bulotta A, Viganò MG, Petrella G, Gianni L, Gregorc V.

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